46366-96-5

Basic information

• Product Name: 4β-Hydroxy-1,3-dimethyl-4α-phenylpiperidin
• CAS NO: 46366-96-5
• Molecular Weight: 205.3
• Mol File: 46366-96-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4β-Hydroxy-1,3-dimethyl-4α-phenylpiperidin(CAS DataBase Reference)
• NIST Chemistry Reference: 4β-Hydroxy-1,3-dimethyl-4α-phenylpiperidin(46366-96-5)
• EPA Substance Registry System: 4β-Hydroxy-1,3-dimethyl-4α-phenylpiperidin(46366-96-5)

Safety Data

• Hazardous Substances Data: 46366-96-5(Hazardous Substances Data)

Upstream product

• 4629-80-5 1,3-dimethyl-4-piperidinone 
• 591-51-5 phenyllithium 

Downstream Products

• 25123-05-1 (-)-β-prodine 

Relevant articles and documents

The morphine-like and nonmorphine-like conformers of prodine opioids

The compounds α-, and β-prodine and their meta hydroxylated analogs were synthesized, resolved, and screened for affinity at opioid receptor subtypes. The compounds primarily have affinity for μ-receptors. The μ-receptor affinities of the nonmorphine-like (+)-enantiomers, which have the greater antinociceptive activity, are reduced by the presence of a meta hydroxyl while the affinities for all opioid receptor subtypes of the morphine-like, but less active, (-)-enantiomers are enhanced or unchanged. Both enantiomers of meta-hydroxylated β-prodine had antagonist activity in the guinea pig ileum assay.