4650-71-9

Basic information

• Product Name: SK 31597
• Synonyms: SK 31597
• CAS NO: 4650-71-9
• Molecular Weight: 358.391
• Mol File: 4650-71-9.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: SK 31597(CAS DataBase Reference)
• NIST Chemistry Reference: SK 31597(4650-71-9)
• EPA Substance Registry System: SK 31597(4650-71-9)

Safety Data

• Hazardous Substances Data: 4650-71-9(Hazardous Substances Data)

Upstream product

• 854678-01-6 4-(3,4-dimethoxy-phenyl)-4-oxo-2-veratroyl-butyric acid ethyl ester 
• 91-16-7 1,2-dimethoxybenzene 
• 543-20-4 succinoyl dichloride 
• 22675-96-3 2-methoxyphenoxy-3',4'-dimethoxyacetophenone 
• 128072-14-0 C₃₀H₄₀N₂O₄ 
• 114914-88-4 (E)-1,4-bis(3,4-dimethoxyphenyl)but-2-ene-1,4-dione 
• 79631-01-9 1,2-dimethoxy-4-<1-<(1,1-dimethylethyl)dimethylsilyloxy>ethenyl>benzene 
• 534-22-5 2-methylfuran 
• 1334498-58-6 S-(2-(3,4-dimethoxyphenyl)-2-oxoethyl) O-ethyl carbonodithioate 
• 67-68-5 dimethyl sulfoxide 
• 1835-02-5 2-Bromo-1-(3,4-dimethoxyphenyl)ethanone 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 31706-95-3 1'-Hydroxymethyleugenol 
• 33731-40-7 1-(3,4-dimethoxyphenyl)prop-2-en-1-one 

Downstream Products

• 4440-92-0 1,4-bis(3,4-dimethoxyphenyl),2,3-dimethylbutane-1,4-dione 
• 134179-59-2 1,4-bis(3,4-dihydroxyphenbyl)butane-1,4-diol 
• 114914-89-5 1,2-bis(3,4-dihydroxybenzoyl)ethane 
• 102454-96-6 1,4-bis-(3,4-dimethoxy-phenyl)-butane-1,4-diol 
• 51487-58-2 1,4-bis(3,4-dimethoxyphenyl)butane 
• 4650-69-5 2,5-Bis-(3,4-dimethoxy-phenyl)-furan 
• 109980-42-9 1-(3',4'-dimethoxyphenyl)-6,7-dimethoxynaphthalene 

Relevant articles and documents

Dihedral-Angle-Controlled Crossover from Static Hole Delocalization to Dynamic Hopping in Biaryl Cation Radicals

In cases of coherent charge-transfer mechanism in biaryl compounds the rates follow a squared cosine trend with varying dihedral angle. Herein we demonstrate using a series of biaryl cation radicals with varying dihedral angles that the hole stabilization

Photochemistry of S -phenacyl xanthates

Various synthetically readily accessible S-phenacyl xanthates are shown to undergo photoinitiated homolytic scission of the C-S bond in the primary step. The resultant fragments, phenacyl and xanthic acid radicals, recombine to form symmetrical 1,4-diketones and xanthogen disulfides, respectively, in high to moderate chemical yields in chemically inert solvents. They can also be efficiently trapped by a hydrogen-atom-donating solvent to give acetophenone and xanthic acid derivatives. The latter compound is in situ thermally converted to the corresponding alcohol in high chemical yields. S-Phenacyl xanthates could thus be utilized as synthetic precursors to the above-mentioned compounds or as photoremovable protecting groups for alcohols in which the xanthate moiety represents a photolabile linker. The photochemically released phenacyl radical fragments efficiently but reversibly add to the thiocarbonyl group of the parent xanthate molecule. The kinetics of this degenerative reversible addition-fragmentation transfer (RAFT)/macromolecular design via the interchange of xanthates (MADIX) mechanism was studied using laser flash photolysis (LFP) and density functional theory (DFT) calculations. The rate constants of the RAFT addition step, kadd ～ 7 × 108 M-1 s-1, and phenacyl radical addition to a double bond of 1,1-diphenylethylene, kadd ～ 108 M-1 s -1, in acetonitrile were experimentally determined by LFP. In addition, photoinitiation of the methyl methacrylate polymerization by S-phenacyl xanthate is demonstrated. The polydispersity index of the resulting poly(methyl methacrylate) was found to be ～1.4. We conclude that S-phenacyl xanthates can serve simultaneously as photoinitiators as well as RAFT/MADIX agents in polymerization reactions.

Substituted furans as inhibitors of the PDE4 enzyme

The synthesis and in vitro activity of a series of substituted furans as a novel structural class of PDE4 inhibitors is described. Comparison of emetic threshold with known PDE4 inhibitors is presented.