467221-26-7Relevant articles and documents
A novel, broad-spectrum antitumor compound containing the 1-hydroxycyclohexa-2,5-dien-4-one group: The disclosure of a new antitumor pharmacophore in protoapigenone 1
Yuan, Qianying,Liu, Ziwei,Xiong, Chaomei,Wu, Liqian,Wang, Jianping,Ruan, Jinlan
, p. 3427 - 3430 (2011)
The synthesis of a new compound 9 containing the 4-hydroxy-2,5- cyclohexadien-1-one system, a key elements toward elucidation of the protoapigenone 1 antitumor pharmacophore, was described. The compound showed potent in vitro antitumor potency with low mi
Synthesis of pyran-4-ones from isoxazoles
Li, Chun-Sing,Lacasse, Edith
, p. 3565 - 3568 (2007/10/03)
A synthesis of mono-, di- and tri-substituted pyran-4-ones from isoxazoles is reported. The isoxazoles can be synthesized from readily available starting materials and undergo a reductive cleavage reaction with Mo(CO)6 to generate enamino keton