4673-45-4

Basic information

• Product Name: 1,3-Dibutyltetrahydro-2(1H)-pyrimidinone
• Synonyms: 1,3-Dibutyltetrahydro-2(1H)-pyrimidinone
• CAS NO: 4673-45-4
• Molecular Formula: C12H24N2O
• Molecular Weight: 212.33176
• Mol File: 4673-45-4.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 316℃
• Flash Point: 122℃
• Appearance: /
• Density: 0.938
• Vapor Pressure: 2.07E-05mmHg at 25°C
• Refractive Index: 1.531
• CAS DataBase Reference: 1,3-Dibutyltetrahydro-2(1H)-pyrimidinone(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dibutyltetrahydro-2(1H)-pyrimidinone(4673-45-4)
• EPA Substance Registry System: 1,3-Dibutyltetrahydro-2(1H)-pyrimidinone(4673-45-4)

Safety Data

• Hazardous Substances Data: 4673-45-4(Hazardous Substances Data)

Usage

Type of drug

Local anesthetic and antiarrhythmic medication

Mechanism of action

Blocks sodium channels in nerve cells, preventing pain signaling

Medical and dental procedures

To numb skin or mucous membranes

Antiarrhythmic treatment

To treat certain types of irregular heartbeats

Available forms

Creams, ointments, and solutions

Tolerance

Generally well-tolerated when used as directed

Side effects

Allergic reactions, skin irritation, and changes in heart rhythm

Precaution

Should be used with caution and under the supervision of a healthcare professional

InChI:InChI=1/C16H17NO/c1-18-16-9-7-15(8-10-16)13-17-12-11-14-5-3-2-4-6-14/h2-10,13H,11-12H2,1H3/b17-13+

Upstream product

• 1852-17-1 3,4,5,6-tetrahydropyrimidin-2(1H)-one 
• 542-69-8 1-iodo-butane 
• 4697-92-1 N,N'-dibutyl-propane-1,3-diamine 

Relevant articles and documents

Process for producing cyclic ureas

A process for producing a cyclic urea is provided. The process comprises reacting a diamine expressed by the formula (II) wherein R represents hydrogen atom or a lower alkyl group and R' represent dimethylene group, a lower alkyl group-substituted dimethylene group, trimethylene group, a lower alkyl group-substituted trimethylene group, tetramethylene group, a lower alkyl group-substituted tetramethylene group, but a case where R represents hydrogen atom and R' represent dimethylene group, a case where R represents hydrogen atom and R' represents a lower alkyl group-substituted dimethylene group and a case where R represent methyl group and R' represents dimethylene group are excluded, with phosgene in the presence of a dehydrochlorinating agent. In the process, the diamine is first converted to its hydrochloride, followed by reacting the hydrochloride with phosgene in water solvent while maintaining a pH of the reaction liquid in the range of 5.0 to 8.0 by said dehydrochlorinating agent to obtain a cyclic urea expressed by the formula (I) STR1 wherein R and R' are each as defined above.