4674-21-9

Basic information

• Product Name: 4,6-dibromo-1,2,3,5-tetramethylbenzene
• Synonyms: 4,6-dibromo-1,2,3,5-tetramethylbenzene
• CAS NO: 4674-21-9
• Molecular Weight: 292.013
• Mol File: 4674-21-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4,6-dibromo-1,2,3,5-tetramethylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 4,6-dibromo-1,2,3,5-tetramethylbenzene(4674-21-9)
• EPA Substance Registry System: 4,6-dibromo-1,2,3,5-tetramethylbenzene(4674-21-9)

Safety Data

• Hazardous Substances Data: 4674-21-9(Hazardous Substances Data)

Upstream product

• 16609-28-2 1,5,5-trimethyl-3-methylenecyclohex-1-ene 
• 7726-95-6 bromine 
• 527-53-7 1,2,3,5-Tetramethylbenzene 
• 3349-15-3 4-bromo-1,2,3,5-tetramethylbenzene 
• 7664-93-9 sulfuric acid 
• 608-72-0 2,4,6-tribromomesitylene 
• 917-54-4 methyllithium 

Downstream Products

• 108-67-8 1,3,5-trimethyl-benzene 
• 33642-07-8 2,6-Dibromo-3,4,5-trimethylbenzylnitrat 

Relevant articles and documents

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Reactions of Alkyl-lithium Compounds with Aryl Halides

Reation of methyl-lithium with tribromophenols and with other aryl polyhalides leads directly to bi- and tri-aryl products. para-Substituents (Y) of 2,6-dibromo-4-Y-phenols promote arylation of substrates by their own lithiation products as Y becomes more electron-withdrawing.An aryne epoxide is not an intermediate in these reactions. 2,4,6-Tribromo-Z-benzenes react to form coupling products when Z can co-ordinate to an introduced ortho-lithium atom or when Z can be directly lithiated.Dimeric aggregation of the organolithium intermediates occurs so as to favor coupling to halogenated substrates.Both polar (ionic) and free-radical pathways are involved.