467426-62-6

Basic information

• Product Name: Cyclopropanecarboxamide, N,N-diethyl-2-methyl-, (1R,2S)-rel- (9CI)
• Synonyms: Cyclopropanecarboxamide, N,N-diethyl-2-methyl-, (1R,2S)-rel- (9CI)
• CAS NO: 467426-62-6
• Molecular Formula: C9H17NO
• Molecular Weight: 155.23738
• Product Categories: AMIDE
• Mol File: 467426-62-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 234.5±7.0 °C(Predicted)
• Appearance: /
• Density: 0.962±0.06 g/cm3(Predicted)
• PKA: -0.46±0.40(Predicted)
• CAS DataBase Reference: Cyclopropanecarboxamide, N,N-diethyl-2-methyl-, (1R,2S)-rel- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopropanecarboxamide, N,N-diethyl-2-methyl-, (1R,2S)-rel- (9CI)(467426-62-6)
• EPA Substance Registry System: Cyclopropanecarboxamide, N,N-diethyl-2-methyl-, (1R,2S)-rel- (9CI)(467426-62-6)

Safety Data

• Hazardous Substances Data: 467426-62-6(Hazardous Substances Data)

Upstream product

• 1950-58-9 (E)-N,N-diethyl-2-butenamide 
• 593-71-5 Chloroiodomethane 

Relevant articles and documents

Stereospecific cyclopropanation of highly substituted C-C double bonds promoted by CrCl2. Stereoselective synthesis of cyclopropanecarboxamides and cyclopropyl ketones

We describe herein a CrCl2-promoted cyclopropanation of α,β-unsaturated amides. This reaction can be carried out on (E)- or (2)-α,β-enamides in which the C-C double bond is di-, tri-, or tetrasubstituted. In all cases the process is completely stereospecific and only a single diastereoisomer is obtained. In addition, cyclopropyl ketones were readily prepared by reaction of the cyclopropanecarboxamides (derived from morpholine) obtained with a range of organolithium compounds. A mechanism has been proposed to explain the cyclopropanation reaction.