468060-26-6

Basic information

• Product Name: 1-[4-(tetrahydro-pyran-2-yloxy)-phenyl]-3-o-tolyl-propenone
• CAS NO: 468060-26-6
• Molecular Weight: 322.404
• Mol File: 468060-26-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-[4-(tetrahydro-pyran-2-yloxy)-phenyl]-3-o-tolyl-propenone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[4-(tetrahydro-pyran-2-yloxy)-phenyl]-3-o-tolyl-propenone(468060-26-6)
• EPA Substance Registry System: 1-[4-(tetrahydro-pyran-2-yloxy)-phenyl]-3-o-tolyl-propenone(468060-26-6)

Safety Data

• Hazardous Substances Data: 468060-26-6(Hazardous Substances Data)

Upstream product

• 16162-69-9 1-(4-(tetrahydro-2H-pyran-2-yloxy)phenyl)ethanone 
• 529-20-4 2-methylphenyl aldehyde 
• 110-87-2 3,4-dihydro-2H-pyran 
• 99-93-4 4-Hydroxyacetophenone 

Downstream Products

• 103826-25-1 2-methyl,4'-hydroxychalcone 

Relevant articles and documents

Synthesis of some pyrazole derivatives and preliminary investigation of their affinity binding to P-glycoprotein

A series of substituted pyrazolines were synthesized and evaluated for their anticancer activity and for their ability to inhibit P-glycoprotein- mediated multidrug resistance by direct binding to a purified protein domain containing an ATP-binding site and a modulator interacting region. Compounds 2a and e have been found to bind to P-glycoprotein with greater affinity.