468065-21-6

Basic information

• Product Name: hexaazidoneomycin B
• Synonyms: hexaazidoneomycin B
• CAS NO: 468065-21-6
• Molecular Weight: 770.636
• Mol File: 468065-21-6.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: hexaazidoneomycin B(CAS DataBase Reference)
• NIST Chemistry Reference: hexaazidoneomycin B(468065-21-6)
• EPA Substance Registry System: hexaazidoneomycin B(468065-21-6)

Safety Data

• Hazardous Substances Data: 468065-21-6(Hazardous Substances Data)

Upstream product

• 4146-30-9 neomycin B trisulfate 
• 25389-98-4 neomycin B sulphate 
• 119-04-0 neomycin B 

Downstream Products

• 688744-66-3 1,3,2',6'-tetraazido-3',4'-di-O-acetylneamine 
• 671809-10-2 1,3,2′,6′-tetraazidoneamine 
• 182554-04-7 1,3,2′,6′-tetraazido-6,3′,4′-tri-O-acetylneamine 
• 340270-00-0 2,5,3′,4′-tetra-O-acetyl-2′,6′-diazido-1-phenylthio-β-neobiosamine 

Relevant articles and documents

APROSAMINE DERIVATIVES

The present disclosure provides compounds for the treatment of medical disorders caused by bacteria, in particular aprosamine derivatives for the treatment of bacterial infections.

Conjugated antimicrobial agents

Provided herein are antimicrobial conjugates of two antibiotic agents, exhibiting improved activity also against resistant bacteria, compared to each of the agents separately or their mixture, and having substantially no resistance emerged thereagainst, as well as processes for preparation the same, compositions containing the same, and uses thereof in medical treatments against pathogenic microorganisms. The disclosed antimicrobial conjugates are composed of aminoglycosides and non-ribosomal active antibiotics. Some of the antimicrobial conjugates are prepared via “click” chemistry.

Design, synthesis, and evaluation of novel fluoroquinolone - Aminoglycoside hybrid antibiotics

A series of new hybrid structures containing fluoroquinolone (ciprofloxacin) and aminoglycoside (neomycin) antibiotics linked via 1,2,3-triazole moiety were designed and synthesized, and their antibacterial activities were determined against both Gram-neg