4682-54-6 Usage
Description
(4alpha,12xi)-8-oxo-12,13-epoxytrichothec-9-en-4-yl acetate is a type of trichothecene mycotoxin produced by certain species of fungi. It has a unique chemical structure with an epoxy ring and an acetate group, and is likely to have similar toxic properties as other trichothecenes. Due to its potential health risks, exposure to this chemical should be avoided, and proper precautions should be taken when handling or working with materials that may be contaminated with it.
Uses
Used in Research Applications:
(4alpha,12xi)-8-oxo-12,13-epoxytrichothec-9-en-4-yl acetate is used as a research tool for studying the toxic effects of trichothecene mycotoxins on human health and the immune system. Its unique chemical structure allows researchers to investigate the mechanisms of action and potential countermeasures against these toxins.
Used in Environmental Monitoring:
(4alpha,12xi)-8-oxo-12,13-epoxytrichothec-9-en-4-yl acetate can be used as a biomarker for detecting the presence of trichothecene-producing fungi in the environment. This can help in assessing the risk of exposure to these toxins and implementing appropriate safety measures.
Used in Agricultural Applications:
(4alpha,12xi)-8-oxo-12,13-epoxytrichothec-9-en-4-yl acetate can be used in the development of strategies to control the growth of trichothecene-producing fungi in crops and prevent contamination of food products. This can help ensure food safety and reduce the risk of mycotoxin-related health issues.
Used in Pharmaceutical Development:
Although (4alpha,12xi)-8-oxo-12,13-epoxytrichothec-9-en-4-yl acetate is toxic, its unique chemical structure may provide insights into the development of new pharmaceuticals with similar mechanisms of action. Researchers can explore the potential therapeutic applications of this compound or its derivatives, while also working to mitigate its toxic effects.
Check Digit Verification of cas no
The CAS Registry Mumber 4682-54-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,6,8 and 2 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 4682-54:
(6*4)+(5*6)+(4*8)+(3*2)+(2*5)+(1*4)=106
106 % 10 = 6
So 4682-54-6 is a valid CAS Registry Number.
4682-54-6Relevant articles and documents
Synthesis, antifungal activity, and QSAR study of novel trichodermin derivatives
Cheng, Jing-Li,Zheng, Min,Yao, Ting-Ting,Li, Xiao-Liang,Zhao, Jin-Hao,Xia, Min,Zhu, Guo-Nian
, p. 47 - 55 (2015)
In an attempt to discover more potential antifungal agents, in this study, 21 novel trichodermin derivatives containing conjugated oxime ester (5a-5u) were designed and synthesized and were screened for in vitro antifungal activity. The bioassay tests sho
Synthesis and antifungal activity of trichodermin derivatives
Cheng, Jing Li,Zhou, Yong,Zhao, Jin Hao,Zhang, Chulong,Lin, Fu Cheng
scheme or table, p. 1037 - 1040 (2011/10/05)
A series of derivatives were synthesized from trichodermin (1) which was an antifungal metabolite produced by Trichoderma taxi sp. nov. Their structures were confirmed by 1H NMR, MS spectrum. Their antifungal activities were evaluated in vitro. The preliminary structure activity relationships (SAR) results indicated that the double bond, epoxide moiety and ester group were main pharmacophore elements, the stereochemistry of C4 position played a key role as well, and the compounds 1e-1g displayed stronger antifungal activity against Magnaporthe grisea than 1.
