468751-39-5

Basic information

• Product Name: Dibenzo[a,e]cyclooctene, 5,11 - bis(phenylsulfonyl)
• Synonyms: Dibenzo[a,e]cyclooctene, 5,11 - bis(phenylsulfonyl)
• CAS NO: 468751-39-5
• Molecular Formula: C28H20O4S2
• Molecular Weight: 484.59
• Mol File: 468751-39-5.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Dibenzo[a,e]cyclooctene, 5,11 - bis(phenylsulfonyl)(CAS DataBase Reference)
• NIST Chemistry Reference: Dibenzo[a,e]cyclooctene, 5,11 - bis(phenylsulfonyl)(468751-39-5)
• EPA Substance Registry System: Dibenzo[a,e]cyclooctene, 5,11 - bis(phenylsulfonyl)(468751-39-5)

Safety Data

• Hazardous Substances Data: 468751-39-5(Hazardous Substances Data)

Usage

General Description

Dibenzo[a,e]cyclooctene, 5,11 - bis(phenylsulfonyl) is a chemical compound that is commonly used in organic synthesis and as a reagent in the preparation of various organic compounds. It belongs to the class of dibenzocyclooctanes, which are a group of organic compounds containing two benzene rings fused to a cyclooctane ring. The bis(phenylsulfonyl) group in this compound makes it useful for creating symmetrical and highly functionalized molecules. This chemical is primarily utilized in the pharmaceutical and chemical industries for the synthesis of biologically active compounds and advanced organic materials. Due to its versatile reactivity and potential for creating complex molecules, dibenzo[a,e]cyclooctene, 5,11 - bis(phenylsulfonyl) is an important intermediate in organic chemistry.

Upstream product

• 468751-38-4 ortho-(phenylsulfonylmethyl)benzaldehyde 
• 529-19-1 2-Methylbenzonitrile 
• 82651-72-7 ortho-(phenylsulfonylmethyl)benzonitrile 
• 22115-41-9 2-(bromomethyl)benzonitrile 
• 873-55-2 sodium benzenesulfonate 

Downstream Products

• 1253203-72-3 1,8-dibenzyl-1,8-dihydrodibenzo[3,4:7,8]cycloocta[1,2-d:5,6-d']bis([1,2,3]triazole) 
• 1253203-73-4 C₃₀H₂₂N₆ 
• 53397-65-2 sym-dibenzo-1,5-cyclooctadiene-3,7-diyne 

Relevant articles and documents

METHODS AND REAGENTS FOR CROSS-LINKING CELLULAR DNA AND RNA VIA STRAIN-PROMOTED DOUBLE-CLICK REACTIONS

The present invention relates to new reagents and methods for modifying nucleic acids where an azide-containing nucleoside or nucleotide derivative is applied to living cells followed by a nitrogenous derivative of dibenzo-1,5-cyclooctadiyne (CODY). The azide- containing derivative is metabolically incorporated into cellular DNA and/or RNA, and the CODY derivative undergoes a strain-promoted double-click reaction to give nucleic acid – nucleic acid cross links, and/or optionally, in the presence of an exogenously added azide (X- N3); to give nucleic acid – "X" cross links.

Substituted 5,6,11,12-tetradehydrodibenzo[ a, e ]cyclooctenes: Syntheses, properties, and DFT studies of substituted sondheimer-wong diynes

Highly strained cyclic acetylenes 5,6,11,12-tetradehydrodibenzo[a,e]cyclooctenes (Sondheimer-Wong diynes) having various substituents on their benzene rings were synthesized successfully by one-pot treatment of the corresponding formyl sulfones with diethyl chlorophosphate/lithium hexamethyldisilazide (LiHMDS) and then lithium diisopropylamide (LDA). When mixtures of two types of formyl sulfones bearing different substituents were subjected to this protocol, the unsymmetrically substituted Sondheimer-Wong diynes could be synthesized in a stepwise manner by isolation of the heterocoupled vinyl sulfone intermediates followed by their treatment with LDA. The UV-vis absorption spectra and cyclic voltammograms of the substituted Sondheimer-Wong diynes were recorded. The electronic effect of substituents on the diynes was investigated in their click reactions and nucleophilic and electrophilic additions.