4695-07-2Relevant articles and documents
Thiol-Containing Metallo-β-Lactamase Inhibitors Resensitize Resistant Gram-Negative Bacteria to Meropenem
Tehrani, Kamaleddin Haj Mohammad Ebrahim,Martin, Nathaniel I.
, p. 711 - 717 (2017/10/23)
The prevalence of infections caused by metallo-β-lactamase (MBL) expressing Gram-negative bacteria has grown at an alarming rate in recent years. Despite the fact that MBLs can deactivate virtually all β-lactam antibiotics, there are as of yet no approved
Chiroptical Properties of 2,2'-Dithio- and 2,2'-Diselenobisacetic Acids
Ringdahl, Bjoern,Craig, J. Cymerman,Fredga, Arne,Bonner, William A.
, p. 467 - 472 (2007/10/02)
Circular dichroism (CD) studies of 2,2'-dithiobisacetic acids substituted with alkyl or phenyl groups and their diselenide analogues show that considerable interaction occurs between the disulfide (or diselenide) chromophore and the carboxyl or phenyl groups, giving rise to intense Cotton effects (CE's) which dominate the near UV region of CD spectrum.In contrast, when the disulfide and carboxyl chromophores are separated by two carbon atoms, each chromophore gives a separate CE of normal intensity at the expected wavelength with no evidence of interaction between them.