4698-39-9 Usage
Description
(E)-Doxepin hydrochloride is a tricyclic antidepressant medication that functions by influencing specific chemicals in the brain, such as serotonin and norepinephrine. It is recognized for its effectiveness in treating symptoms of depression and anxiety disorders, as well as insomnia and other sleep disorders. The medication is available in capsule or liquid suspension form and is typically administered orally once daily in the evening, following the guidance of a healthcare professional. Dosage adjustments may be necessary to achieve the most effective and safe treatment level for each individual. While common side effects include drowsiness, dry mouth, and dizziness, it is crucial to consult with a medical expert before initiating this medication due to potential interactions with other substances or medications.
Uses
Used in Pharmaceutical Industry:
(E)-Doxepin hydrochloride is used as an antidepressant for treating symptoms of depression and anxiety disorders. It helps in managing the emotional and psychological effects of these conditions by modulating the levels of serotonin and norepinephrine in the brain.
Used in Sleep Aid Applications:
(E)-Doxepin hydrochloride is used as a sleep aid for treating insomnia and other sleep disorders. It assists in improving sleep quality and duration by addressing the underlying issues that contribute to sleep disturbances.
Used in Medical Treatments:
(E)-Doxepin hydrochloride is used as a therapeutic agent to be taken exactly as directed by a doctor. The medication may require dosage adjustments to find the most effective and safe level for each individual, ensuring optimal treatment outcomes.
Check Digit Verification of cas no
The CAS Registry Mumber 4698-39-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,6,9 and 8 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 4698-39:
(6*4)+(5*6)+(4*9)+(3*8)+(2*3)+(1*9)=129
129 % 10 = 9
So 4698-39-9 is a valid CAS Registry Number.
InChI:InChI=1/C21H25NO.ClH/c1-21(2,22(3)4)14-13-18-17-10-6-5-9-16(17)15-23-20-12-8-7-11-19(18)20;/h5-13H,14-15H2,1-4H3;1H/b18-13+;
4698-39-9Relevant articles and documents
Synthetic method of doxepin hydrochloride
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Paragraph 0036; 0047-0049; 0054-0055; 0060-0061; 0066-0067, (2020/12/30)
The invention discloses a synthetic method of doxepin hydrochloride. The synthetic method comprises the following steps: using N, N-dimethyl-3-chloropropylamine as an initial raw material, carrying out Grignard reaction, carrying out addition reaction on the reaction product and 6, 11-dihydrodibenzo [b, e] oxepine-11-ketone, and sequentially carrying out elimination reaction and salifying reactionto synthesize the final product. According to the method, high-purity doxepin hydrochloride can be obtained through four-step synthesis, a substitution reaction is not needed, and the yield of the prepared product is high. Compared with the existing synthesis process, the method has the advantages of few synthesis steps, simple process, short production period, low cost and the like.
