471259-71-9

Basic information

• Product Name: Benzenepropanoic acid, b-aMino-, hydrochloride
• CAS NO: 471259-71-9
• Molecular Formula: C₉H₁₁NO₂*ClH
• Molecular Weight: 201.65008
• Mol File: 471259-71-9.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzenepropanoic acid, b-aMino-, hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanoic acid, b-aMino-, hydrochloride(471259-71-9)
• EPA Substance Registry System: Benzenepropanoic acid, b-aMino-, hydrochloride(471259-71-9)

Safety Data

• Hazardous Substances Data: 471259-71-9(Hazardous Substances Data)

Upstream product

• 40638-98-0 (R/S)-3-(acetylamino)-3-phenylpropanoic acid 
• 126378-84-5 (RS)-2-phenyl-2,3-dihydro-1H-pyridin-4-one 
• 864871-38-5 diethyl 2-(1-(N-tert-butoxycarbonylamino)-1-phenylmethyl)malonate 
• 19909-81-0 tris(p-methoxyphenyl)phosphite 
• 271600-36-3 N-[phenyl(toluene-4-sulfonyl)methyl]tert-butoxycarboxyamide 
• 214626-96-7 (RS)-1-benzoyl-2-phenyl-2,3-dihydro-1H-pyridin-4-one 
• 92653-04-8 ethyl 2-(acetamido(phenyl)-methyl)-3-oxobutanoate 
• 100-52-7 benzaldehyde 

Downstream Products

• 480443-48-9 3-pent-4-enoylamino-3-phenyl-propionic acid 
• 29754-04-9 ethyl 3-amino-3-phenylpropanoate hydrochloride 
• 528891-45-4 3-acryloylamino-3-phenyl-propionic acid 
• 528891-43-2 2-[2-(3-acryloylamino-3-phenyl-propionylamino)-3-phenyl-propionylamino]-4-methyl-pentanoic acid methyl ester 
• 528891-44-3 N-(2-{1-[1-(3-bromo-benzylcarbamoyl)-3-methyl-butylcarbamoyl]-2-phenyl-ethylcarbamoyl}-1-phenyl-ethyl)-acrylamide 
• 6300-95-4 6-phenyldihydropyrimidine-2,4(1H,3H)-dione 
• 14593-04-5 3-amino-3-phenyl-1-propanol 

Relevant articles and documents

New access to racemic β3-amino acids

A general simple procedure having the potential for large scale preparations of racemic β3-amino acids has been developed. The procedure involves base-catalyzed Michael-type addition of sodium diethyl malonate to N-Boc-α-amidoalkyl-p-tolyl sulfones in tetrahydrofuran. Hydrolysis of the adducts by refluxing with 6 M aqueous hydrochloric acid affords β3-amino acid hydrochlorides in high yield and excellent purity.

Synthesis of small cyclic peptides via intramolecular Heck reactions

Tripeptides having a 3-bromobenzyl group at the C-termini and an acryloyl group at the N termini undergo efficient intramolecular Heck reactions to afford the corresponding cyclic peptides in good yields. Synthesis of two such peptides is discussed.