47136-83-4

Basic information

• Product Name: 3'-monophosphate of cytidine
• Synonyms: 3'-monophosphate of cytidine
• CAS NO: 47136-83-4
• Molecular Weight: 321.183
• Mol File: 47136-83-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3'-monophosphate of cytidine(CAS DataBase Reference)
• NIST Chemistry Reference: 3'-monophosphate of cytidine(47136-83-4)
• EPA Substance Registry System: 3'-monophosphate of cytidine(47136-83-4)

Safety Data

• Hazardous Substances Data: 47136-83-4(Hazardous Substances Data)

Upstream product

• 47791-58-2 C₁₈H₂₃N₅O₁₃P^(1-) 
• 50574-59-9 cytidine 2′,3′-cyclic monophosphate 

Relevant articles and documents

Hydrolysis of diribonucleoside monophosphate diesters assisted by a manganese(II) complex

An Mn2+ complex with 2,2′:6′,2″-terpyridine (terpy) was found to promote the hydrolysis of NpN (NpN = diribonucleoside monophosphate diester) efficiently at pH 7.0 and 50 °C under ambient conditions. The structure of the Mn2+ complex involving a phosphodiester molecule, [(terpy)(dpp)MnII(μ-dpp) 2MnII(dpp)(terpy)], dpp = diphenyl phosphate anion, was established by X-ray crystallography, and the coordination mode of Mn 2+ to a phosphodiester molecule was considered.

α-Cyclodextrin-Catalyzed Regioselective P-O(2') Cleavages of 2',3'-Cyclic Monophosphates of Ribonucleosides

Regioselective P-O(2') cleavages of 2',3'-cyclic monophosphates of cytidine (1a), uridine (1b), adenosine (1c), and guanosine (1d) to the corresponding 3'-monophosphates (IIIa-d) are achieved at pH 11.08, 20 deg C by α-cyclodextrin (α-CyD) as catalyst.The selectivities asymptotically increase with increasing concentration of α-CyD, attaining 98, 94, 76, and 67percent for the cleavages of Ia-d, respectively, at the concentration of 0.05 M α-CyD.In the absence of α-CyD, however, significant concurrent cleavages of the P-O(3') bonds take place and the selectivities for IIIa-d are only 47, 50, 54, and 52percent.The rate of the P-O(2') cleavage of Ia in the α-CyD-Ia complex is 14 times as large as that of free Ia, and the rate of the P-O(3') cleavage in the complex is virtually zero. β- and γ-CyDs show no regioselective catalyses. 1H NMR spectroscopy indicates that the α-CyD-Ia and -Ib complexes are formed by hydrogen bondings and I's are located on the secondary hydroxyl side of the cavity of α-CyD.The selective cleavages of ribonucleotide dimers CpC, CpU, CpA, and CpG to IIIa are also successfully carried out by α-CyD as catalyst.