4714-14-1

Basic information

• Product Name: 1,2-DIPHENYLCHLOROETHANE
• CAS NO: 4714-14-1
• Molecular Formula: C₁₄H₁₃Cl
• Molecular Weight: 216.71
• Mol File: 4714-14-1.mol
• Article Data: 26

Chemical Properties

• Boiling Point: 295.3°Cat760mmHg
• Flash Point: 128.3°C
• Density: 1.11g/cm³
• CAS DataBase Reference: 1,2-DIPHENYLCHLOROETHANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-DIPHENYLCHLOROETHANE(4714-14-1)
• EPA Substance Registry System: 1,2-DIPHENYLCHLOROETHANE(4714-14-1)

Safety Data

• Hazardous Substances Data: 4714-14-1(Hazardous Substances Data)

Usage

Physical state

White, crystalline solid

Solubility

Insoluble in water

Odor

Slightly sweet

Toxicity

Highly toxic

Persistence

Persistent organic pollutant

Former use

Widely used as a pesticide

Exposure routes

Inhalation, ingestion, or skin contact

Health effects

Damage to the nervous system, liver, and kidneys

Environmental impact

Long half-life in the environment

Regulatory status

Heavily restricted and phased out in many countries

Current concern

Legacy pollutant due to its persistence in the environment

Upstream product

• 103-29-7 1,1'-(1,2-ethanediyl)bisbenzene 
• 1125-80-0 3-methylisoquinoline 
• 100-44-7 benzyl chloride 
• 10152-76-8 allylmethyl sulfide 
• 925-89-3 Prop-1-en-1-thiol 
• 74-88-4 methyl iodide 
• 4460-46-2 3-chloro-3-phenyl-3H-diazirine 
• 100-42-5 styrene 
• 100-34-5 benzene diazonium chloride 
• 7647-01-0 hydrogenchloride 
• 100-51-6 benzyl alcohol 
• 7664-41-7 ammonia 
• 7705-08-0 iron(III) chloride 
• 981-18-0 triphenyl(phenylazo)methane 

Downstream Products

• 102474-38-4 benzyl-bibenzyl-α-yl sulfide 
• 79560-59-1 2-methyl-6-(2,3-diphenylpropyl) pyridine 
• 103-30-0 (E)-1,2-diphenyl-ethene 
• 83237-43-8 2,2-dimethyl-5,6-diphenylhexan-3-one 
• 95622-47-2 (+/-)-erythro-2.3.4-triphenyl-butyric acid ethyl ester 
• 88144-93-8 1-(1,2-diphenylethyl)piperazine 
• 937808-26-9 tert-butyl 4-(1,2-diphenylethyl)piperazine-1-carboxylate 
• 1198172-01-8 (S)-2-(1,2-diphenylethyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 41822-67-7 (R)-1,2-diphenylethanol 
• 63180-94-9 (S)-1,2-diphenylethanol 
• 1433777-58-2 (R)-5-(4-methoxyphenyl)-1,2-diphenylpentan-3-one 
• 645-49-8 cis-stilben 
• 65792-00-9 phenyl-2-phenylethyl sulfide 
• 61668-43-7 (1-nitroethane-1,2-diyl)dibenzene 

Relevant articles and documents

Ruthenium-Catalyzed Reductive Arylation of N-(2-Pyridinyl)amides with Isopropanol and Arylboronate Esters

A new three-component reductive arylation of amides with stable reactants (iPrOH and arylboronate esters), making use of a 2-pyridinyl (Py) directing group, is described. The N-Py-amide substrates are readily prepared from carboxylic acids and PyNH2, and the resulting N-Py-1-arylalkanamine reaction products are easily transformed into the corresponding chlorides by substitution of the HN-Py group with HCl. The 1-aryl-1-chloroalkane products allow substitution and cross-coupling reactions. Therefore, a general protocol for the transformation of carboxylic acids into a variety of functionalities is obtained. The Py-NH2 by-product can be recycled.

Hydrogenated acridine derivative and its application

The invention relates to the field of chemical synthesis, and particularly relates to a compound with the general formula being Y-L-X and an application of the compound serving as a calcium channel blocking agent or/and an acetylcholinesterase inhibitor. The compound with the general formula being Y-L-X can be used for adjusting calcium homeostasis and treating cardiovascular diseases, stroke or dementia.

Nickel-catalyzed asymmetric reductive cross-coupling between vinyl and benzyl electrophiles

A Ni-catalyzed asymmetric reductive cross-coupling between vinyl bromides and benzyl chlorides has been developed. This method provides direct access to enantioenriched products bearing aryl-substituted tertiary allylic stereogenic centers from simple, stable starting materials. A broad substrate scope is achieved under mild reaction conditions that preclude the pregeneration of organometallic reagents and the regioselectivity issues commonly associated with asymmetric allylic arylation.