47169-38-0Relevant articles and documents
Halogenated Phenols for Diagnostics, Antioxidant Protection and Drug Delivery
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Paragraph 0287, (2018/05/16)
The present invention provides compositions and methods for the targeted delivery, release and/or formation of a drug compound at a target site(s) within the body of an individual, such as a diseased and/or inflamed tissue in the body of the individual. These compositions may comprise a halogenated phenol ring cleavably linked to a core structure of a drug compound. Due to the variety of substituents that may be utilized in forming the different types of linkages, numerous examples of drug compounds linked to a halogenated phenol ring are proposed. The present invention further provides compositions comprising halogenated phenol starting compounds that do not undergo cleavage during a dehalogenation reaction to form a drug compound in a targeted tissue when administered to an individual. Methods of administering these non-cleaving compounds are further provided.
3,3 'dinitroglycerin-4-, 4' -dihydroxydiphenyl ether and purification of 3, dinitroglycerin 3 '-4-, 4' -dihydroxydiphenyl ether production method
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Paragraph 0020; 0023; 0024, (2018/10/16)
PROBLEM TO BE SOLVED: To provide a method for refining 3,3'-dinitro-4,4'-dihydroxydiphenyl ether with high productivity applicable as an industrial production method.SOLUTION: A crude product of 3,3'-dinitro-4,4'-dihydroxydiphenyl ether is subjected to suspension washing with acetone or an acetone aqueous solution. The resulting suspension is filtered, washed and dried to obtain a 3,3'-dinitro-4,4'-dihydroxydiphenyl ether composition reduced in the content of impurities.
Oppi briefs practical and efficient synthesis of 4,4'-dihydroxy-3,3'- dinitrodiphenyl ether and 1,3-bis(4-hydroxy-3-nitrophenoxy)benzene in aqueous alkaline medium
Imoto, Mitsutaka,Takeda, Motonori,Tamaki, Akihiro,Taniguchi, Hisaji,Mizuno, Kazuhiko
scheme or table, p. 161 - 167 (2010/09/05)
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