47195-07-3 Usage
Description
d-Cocaine, the active stereoisomer of the popular recreational drug cocaine, is a potent central nervous system stimulant. It functions by inhibiting the reuptake of neurotransmitters such as dopamine, norepinephrine, and serotonin, which results in elevated levels of these chemicals and induces sensations of euphoria and heightened alertness. Despite its stimulating effects, d-Cocaine poses a significant risk of addiction and can lead to severe health issues, including cardiovascular problems, respiratory complications, and neurological damage. As a consequence of its addictive and harmful properties, d-Cocaine is classified as a controlled substance and is prohibited from possession or distribution in the majority of countries.
Uses
Used in Pharmaceutical Industry:
d-Cocaine is used as a local anesthetic for minor surgical procedures, dental work, and other medical applications that require numbing of a specific area. Its ability to block nerve conduction and reduce pain sensation makes it a valuable component in certain medical treatments.
Used in Research:
d-Cocaine serves as a research tool in scientific studies aimed at understanding the mechanisms of addiction, neurotransmitter function, and the effects of stimulants on the brain and body. This helps in the development of potential treatments and interventions for substance abuse and related conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 47195-07-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,7,1,9 and 5 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 47195-07:
(7*4)+(6*7)+(5*1)+(4*9)+(3*5)+(2*0)+(1*7)=133
133 % 10 = 3
So 47195-07-3 is a valid CAS Registry Number.
InChI:InChI=1/C17H21NO4/c1-18-12-8-9-13(18)15(17(20)21-2)14(10-12)22-16(19)11-6-4-3-5-7-11/h3-7,12-15H,8-10H2,1-2H3/t12-,13+,14-,15+/m1/s1
47195-07-3Relevant articles and documents
A practical synthesis of (+)-cocaine
Lewin,Naseree,Carroll
, p. 19 - 21 (1987)
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Asymmetric total synthesis of (S)-(+)-cocaine and the first synthesis of cocaine C-1 analogs from N -sulfinyl β-amino ester ketals
Davis, Franklin A.,Theddu, Naresh,Edupuganti, Ram
supporting information; experimental part, p. 4118 - 4121 (2010/11/17)
Sulfinimine-derived α,β-unsaturated pyrrolidine nitrones, on heating with Al(O-t-Bu)3, undergo a highly stereoselective intramolecular [3 + 2] cycloaddition to give tricyclic isoxazolidines, which are transformed in three-steps to give C-1 substituted cocaine analogs.
Total synthesis of (+)-cocaine via desymmetrization of a meso-dialdehyde
Mans, Douglas M.,Pearson, William H.
, p. 3305 - 3308 (2007/10/03)
(Chemical Equation Presented) The total synthesis of (+)-cocaine is described. An extension of the recently reported proline catalyzed intramolecular enol-exo-aldol reaction to a meso-dialdehyde provided the tropane ring skeleton directly with good enanti
