4728-07-8

Basic information

• Product Name: 1,3-dioxan-5-ylmethanol
• CAS NO: 4728-07-8
• Molecular Formula: C₅H₁₀O₃
• Molecular Weight: 118.1311
• Mol File: 4728-07-8.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 199.6°C at 760 mmHg
• Flash Point: 91.3°C
• Density: 1.102g/cm³
• Vapor Pressure: 0.0847mmHg at 25°C
• Refractive Index: 1.433
• CAS DataBase Reference: 1,3-dioxan-5-ylmethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-dioxan-5-ylmethanol(4728-07-8)
• EPA Substance Registry System: 1,3-dioxan-5-ylmethanol(4728-07-8)

Safety Data

• Hazardous Substances Data: 4728-07-8(Hazardous Substances Data)

Usage

Physical state

Colorless liquid

Solubility

Soluble in water

Usage

Commonly used as a solvent in various industrial processes

Applications

Potential applications in pharmaceuticals, agrochemicals, and fine chemicals

Hazard

Can be hazardous if not used properly

Safety precautions

Handle with care

Upstream product

• 5703-44-6 1,3-dioxane-5-carboxylic acid 
• 51335-73-0 5,5-diethoxycarbonyl-1,3-dioxane 
• 100351-22-2 1,3-dioxane-5,5-dicarboxylic acid 
• 109-87-5 Dimethoxymethane 
• 4704-94-3 2-hydroxymethyl-1,3-propanediol 

Downstream Products

• 61728-99-2 5-bromomethyl-1,3-dioxane 
• 1301764-26-0 {[(1,3-dioxan-5-ylmethoxy)carbonyl]oxy}methyl (4S,5S)-5-((2S)-2-{[(3-amino-2,2-dimethyl-3-oxopropyl)amino]carbonyl}-3-methylbutyl)-4-{(2S)-2-[4-methoxy-3-(3-methoxypropoxy)benzyl]-3-methylbutyl}-1,3-oxazolidine-3-carboxylate 

Relevant articles and documents

PYRAZOLOTHIAZOLE COMPOUND

A compound represented by the formula (I) or pharmacologically acceptable salt thereof exhibits an excellent CRF receptor antagonism wherein X is a nitrogen atom or CH; R1 is -A11-A12; A11 is a single bond or a C1-6 alkylene group; A12 is a hydrogen atom, a C1-6 alkyl group or a C3-6 cycloalkyl group, etc.; R2 is -A21-A22; A21 is a single bond or a C1-6 alkylene group; A22 is a hydrogen atom, a C1-6 alkyl group, a C3-6 cycloalkyl group, a non-aromatic heterocyclic group, or a heteroaryl group, etc.; R3 is a C 1-6 alkyl group, a C3-6 cycloalkyl group, a C1-6 alkoxy group, a C3-6 cycloalkoxy C1-6 alkyl group, di-C1-6 alkyl amino group, a halogen atom, a cyano group, a formyl group, or a carboxyl group, etc; R4 is a hydrogen atom or a C1-6 alkoxy group; R5 is a halogen atom, a C1-6 alkyl group, or a C1-6 alkoxy group; R6 is a hydrogen atom, a C1-6 alkyl group, a C1-6 alkoxy group, a C1-6 alkylthio group, or a C1-6 alkyl sulfinyl group etc.; and R7 is a C1-6 alkyl group, a C1-6 alkoxy group, or a C1-6 alkylthio group

Benzimidazole compound

An object of the present invention is to provide a novel chemical compound useful as a therapeutic or prophylactic agent for acid-related diseases, having an excellent inhibitory effect against gastric acid secretion, an excellent effect of maintaining the inhibitory effect against gastric acid secretion, thereby maintaining intragastric pH high for a long time, and having more safety and appropriate physicochemical stability. Provided is a compound represented by where R1 and R3 may be the same or different and each represent a hydrogen atom or a C1-C6 alkyl group; R2 represents (5,5-dimethyl-1,3-dioxan-2-yl)methoxy group, 5,7-dioxaspiro[2.5]oct-6-ylmethoxy group, 1,5,9-trioxaspiro[5.5]undec-3-ylmethoxy group, or (2,2-dimethyl-1,3-dioxan-5-yl)methoxy group; R4, R5, R6 and R7 represent a hydrogen atom, halogen atom, C1-C6 alkyl group, C1-C6 haloalkyl group, C1-C6 alkoxy group or C1-C6 haloalkoxy group; and W1 represents a single bond, methylene or ethylene group, a salt thereof or a solvate of these.