47285-65-4

Basic information

• Product Name: (S)-1-(2-Benzyloxycarbonylamino-acetyl)-piperidine-2-carboxylic acid
• CAS NO: 47285-65-4
• Molecular Weight: 320.345
• Mol File: 47285-65-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-1-(2-Benzyloxycarbonylamino-acetyl)-piperidine-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-(2-Benzyloxycarbonylamino-acetyl)-piperidine-2-carboxylic acid(47285-65-4)
• EPA Substance Registry System: (S)-1-(2-Benzyloxycarbonylamino-acetyl)-piperidine-2-carboxylic acid(47285-65-4)

Safety Data

• Hazardous Substances Data: 47285-65-4(Hazardous Substances Data)

Upstream product

• 2899-60-7 Cbz-Gly-ONSuc 
• 3105-95-1 pipecolinic acid 
• 1138-80-3 N-(Benzyloxycarbonyl)glycine 
• 501-53-1 benzyl chloroformate 

Relevant articles and documents

Conformational analysis of β-turn structure in tetrapeptides containing proline or proline analogs

In order to evaluate the influence of cyclic secondary amino acids on the stability of β-turn structure, we have prepared Ac-Gly-L-Xxx-L-Leu-Gly-N(CH3)2 (Xxx = Aze, 4-membered ring: 1, Xxx = Pro, 5-membered ring: 2, Xxx = Pip, 6-membered ring: 3). The NOE cross peaks that support β-turn structure were observed in 1-3. The NOE cross peak between both terminals of the synthetic peptides, however, was observed only in the NOESY spectra of 2. This result indicates that 5-membered ring side chain in proline plays a very important role in the formation of β-hairpin structure.