473-01-8 Usage
Description
[1R-(1alpha,2beta,5alpha)]-6,6-dimethylbicyclo[3.1.1]heptane-2-methanol, commonly known as menthol, is a bicyclic chemical compound with the molecular formula C10H18O. It features a six-membered ring and a three-membered ring, along with a methyl group and a hydroxyl group. [1R-(1alpha,2beta,5alpha)]-6,6-dimethylbicyclo[3.1.1]heptane-2-methanol has a chiral center with the configuration of (1R, 2S, 5R) and is predominantly found in mint oils.
Uses
Used in Cosmetics:
Menthol is used as a cooling and soothing agent in the cosmetics industry. Its refreshing properties make it an ideal ingredient for various skin care and personal care products.
Used in Medicines:
In the pharmaceutical industry, [1R-(1alpha,2beta,5alpha)]-6,6-dimethylbicyclo[3.1.1]heptane-2-methanol is used as an analgesic and anti-inflammatory agent in topical creams and ointments. Its cooling effect provides temporary relief from pain and inflammation.
Used in Food Additives:
Menthol is also utilized in the food and beverage industry as an additive for its freshening and cooling sensation. It is often used to enhance the flavor and provide a unique sensory experience in products like chewing gum, candies, and beverages.
Used in Oral Hygiene Products:
In the oral care industry, [1R-(1alpha,2beta,5alpha)]-6,6-dimethylbicyclo[3.1.1]heptane-2-methanol is employed for its freshening and cooling effects. It is commonly found in mouthwashes, toothpastes, and breath fresheners to provide a pleasant sensation and maintain oral hygiene.
Check Digit Verification of cas no
The CAS Registry Mumber 473-01-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,7 and 3 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 473-01:
(5*4)+(4*7)+(3*3)+(2*0)+(1*1)=58
58 % 10 = 8
So 473-01-8 is a valid CAS Registry Number.
473-01-8Relevant articles and documents
Visible-Light-Mediated Aerobic Oxidation of Organoboron Compounds Using in Situ Generated Hydrogen Peroxide
Weng, Wei-Zhi,Liang, Hao,Zhang, Bo
, p. 4979 - 4983 (2018/08/24)
A simple and general visible-light-mediated oxidation of organoboron compounds has been developed with rose bengal as the photocatalyst, substoichiometric Et3N as the electron donor, as well as air as the oxidant. This mild and metal-free protocol shows a broad substrate scope and provides a wide range of aliphatic alcohols and phenols in moderate to excellent yields. Notably, the robustness of this method is demonstrated on the stereospecific aerobic oxidation of organoboron compounds.
PS-COD and PS-9-BBN: Polymer-supported reagents for solution-phase parallel synthesis
Revell, Jefferson D.,Doerner, Barbara,White, Peter D.,Ganesan
, p. 831 - 833 (2007/10/03)
(Chemical Equation Presented) 1,5-Cyclooctadiene was deprotonated under LICKOR conditions and reacted with Merrifield resin to afford an immobilized cyclooctadiene in high yield. This polymer is effective as a halogen scavenger, while hydroboration leads to a supported 9-BBN analogue. The latter exhibits similar regioselectivity to 9-BBN in olefin hydroboration.
METHOD OF HYDROBORATING ALCOHOLS AND REDUCING FUNCTIONAL GROUPS USING A RECYCLABLE FLUOROUS BORANE-SULFIDE
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Page 15-17, (2010/02/06)
A method of hydroborating an alkene or alkyne, or reducing an organic functionality, oxidizing primary and secondary alcohols using a fluorous borane-sulfide is disclosed. The method includes regeneration and recycling the fluorous borane-sulfide.