4731-34-4Relevant articles and documents
Tiers,Bovey,Shapiro
, p. 1564 (1962)
Access to Dibenzofurans through Dimerization/Trimerization of Cyclohexanones Followed by Dehydroaromatization
Jiang, Pingyu,Chen, Shanping,Xia, Yi,Zhang, Qingqing,Deng, Guo-Jun
supporting information, p. 8076 - 8081 (2020/11/02)
A novel and efficient method for the synthesis of unsymmetrical substituted dibenzofurans has been developed, which can selectively produce disubstituted dibenzofurans and trisubstituted dibenzofurans products under metal-free conditions. This approach starts from cheap and available nonaromatic cyclohexanones, affording a simple and efficient access to unsymmetrical substituted dibenzofurans.
Competing Pathways in O-Arylations with Diaryliodonium Salts: Mechanistic Insights
Stridfeldt, Elin,Lindstedt, Erik,Reitti, Marcus,Blid, Jan,Norrby, Per-Ola,Olofsson, Berit
supporting information, p. 13249 - 13258 (2017/09/12)
A mechanistic study of arylations of aliphatic alcohols and hydroxide with diaryliodonium salts, to give alkyl aryl ethers and diaryl ethers, has been performed using experimental techniques and DFT calculations. Aryne intermediates have been trapped, and additives to avoid by-product formation originating from arynes have been found. An alcohol oxidation pathway was observed in parallel to arylation; this is suggested to proceed by an intramolecular mechanism. Product formation pathways via ligand coupling and arynes have been compared, and 4-coordinated transition states were found to be favored in reactions with alcohols. Furthermore, a novel, direct nucleophilic substitution pathway has been identified in reactions with electron-deficient diaryliodonium salts.
Green alternative solvents for the copper-catalysed arylation of phenols and amides
Sambiagio, Carlo,Munday, Rachel H.,John Blacker,Marsden, Stephen P.,McGowan, Patrick C.
, p. 70025 - 70032 (2016/08/06)
Investigation of the use of green organic solvents for the Cu-catalysed arylation of phenols and amides is reported. Alkyl acetates proved to be efficient solvents in the catalytic processes, and therefore excellent alternatives to the typical non-green solvents used for Cu-catalysed arylation reactions. Solvents such as isosorbide dimethyl ether (DMI) and diethyl carbonate also appear to be viable possibilities for the arylation of phenols. Finally, a novel copper catalysed acyl transfer process is reported.
