473259-17-5

Basic information

• Product Name: 2-methyl-1-phenyl-piperidine-2-carbonitrile
• Synonyms: 2-methyl-1-phenyl-piperidine-2-carbonitrile
• CAS NO: 473259-17-5
• Molecular Weight: 200.283
• Mol File: 473259-17-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-methyl-1-phenyl-piperidine-2-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-1-phenyl-piperidine-2-carbonitrile(473259-17-5)
• EPA Substance Registry System: 2-methyl-1-phenyl-piperidine-2-carbonitrile(473259-17-5)

Safety Data

• Hazardous Substances Data: 473259-17-5(Hazardous Substances Data)

Upstream product

• 68078-10-4 1-p-phenylpiperidine-2-carbonitrile 
• 74-88-4 methyl iodide 

Downstream Products

• 14142-16-6 (+/-)-2-methyl-1-phenylpiperidine 

Relevant articles and documents

Synthesis of 1-Azaspiroundecane ring system via Thorpe-Ziegler annulation of 2-Cyano-2-(4-Cyano-Tethered) Arylpiperidines

An efficient stereocontrolled route to the spiro[5.5]undecan framework of the histrionicotoxin alkaloids, employing anodic cyanation and Thorpe-Ziegler cyclization as key steps, is described. In the process of gaining information concerning the hydrolysis of the cyanoenamine function in 8, an unexpected intramolecular Friedel-Crafts type reaction provided the aza-fluorene 10.