473610-16-1

Basic information

• Product Name: (2R)-1-Methoxy-3-{4-[(10-{[2-methyl-2'-trifluoromethyl-[1,1'-biphenyl]-4-yl]carbonyl}-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-3-yl)carbonyl]piperazin-1-yl}propan-2-ol
• CAS NO: 473610-16-1
• Molecular Weight: 646.709
• Mol File: 473610-16-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R)-1-Methoxy-3-{4-[(10-{[2-methyl-2'-trifluoromethyl-[1,1'-biphenyl]-4-yl]carbonyl}-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-3-yl)carbonyl]piperazin-1-yl}propan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-1-Methoxy-3-{4-[(10-{[2-methyl-2'-trifluoromethyl-[1,1'-biphenyl]-4-yl]carbonyl}-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-3-yl)carbonyl]piperazin-1-yl}propan-2-ol(473610-16-1)
• EPA Substance Registry System: (2R)-1-Methoxy-3-{4-[(10-{[2-methyl-2'-trifluoromethyl-[1,1'-biphenyl]-4-yl]carbonyl}-10,11-dihydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-3-yl)carbonyl]piperazin-1-yl}propan-2-ol(473610-16-1)

Safety Data

• Hazardous Substances Data: 473610-16-1(Hazardous Substances Data)

Upstream product

• 473260-57-0 10,11-Dihydro-10-[[2-methyl-2'-trifluoromethyl-[1,1'-biphenyl]-4-yl]carbonyl]-3-(1-piperazinylcarbonyl)-5H-pyrrolo[2,1-c][1,4]benzodiazepine hydrochloride salt 
• 544-00-3 3-methyl-N-(3-methylbutyl)-1-butanamine 
• 64491-70-9 R(-)-glycidyl methyl ether 

Relevant articles and documents

Novel tricyclic hydroxy carboxamides and derivatives thereof tocolytic oxytocin receptor antagonists

This invention provides novel substituted tricyclic carboxamides which act as oxytocin receptor competitive antagonists, as well as methods of their manufacture, pharmaceutical compositions and methods of their use in treatment, inhibition, suppression or prevention of preterm labor, dysmenorrhea and endometritis, suppression of labor at term prior to caesarean delivery, and to facilitate antinatal transport to a medical facility. These compounds are also useful in enhancing fertility rates, enhancing survival rates and synchronizing estrus in farm animals; and may be useful in the prevention and treatment of disfunctions of the oxytocin system in the central nervous system including obsessive compulsive disorder (OCD) and neuropsychiatric disorders.