474-60-2

Basic information

• Product Name: Ergostan-3-ol, (3.beta.,5.alpha.,24R)-
• Synonyms: (3β,5α,24R)-Ergostan-3-ol;24β-Methylcholestanol;5α-Cholestan-20(α/β)-Methyl-3β-ol-25,26,26,26,27,27,27-d7;5α-DihydrocaMpesterol;5α-Cholestan-24(RS)-Methyl-3β-ol;Dihydro-Neospongosterol;Ergostan-3-ol, (3.beta.,5.alpha.,24R)-;(3b,5a,24R)-ergostan-3-ol
• CAS NO: 474-60-2
• Molecular Formula: C₂₈H₅₀O
• Molecular Weight: 402.7
• Product Categories: Pharmaceuticals;Steroids;Intermediates & Fine Chemicals
• Mol File: 474-60-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 461.4°C at 760 mmHg
• Flash Point: 193°C
• Appearance: /
• Density: 0.951g/cm³
• Vapor Pressure: 1.87E-10mmHg at 25°C
• Refractive Index: 1.502
• CAS DataBase Reference: Ergostan-3-ol, (3.beta.,5.alpha.,24R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ergostan-3-ol, (3.beta.,5.alpha.,24R)-(474-60-2)
• EPA Substance Registry System: Ergostan-3-ol, (3.beta.,5.alpha.,24R)-(474-60-2)

Safety Data

• Hazardous Substances Data: 474-60-2(Hazardous Substances Data)

Usage

Description

Ergostan-3-ol, (3.beta.,5.alpha.,24R)is a phytosterol, which is a type of steroid derived from plants. It has a specific molecular structure with three hydroxyl groups at the 3.beta., 5.alpha., and 24R positions. Phytosterols are known for their various biological activities and potential health benefits.

Uses

Used in Phytosterol Applications:
Ergostan-3-ol, (3.beta.,5.alpha.,24R)is used as a phytosterol for its potential health benefits, such as helping to lower cholesterol levels and providing anti-inflammatory effects.
Used in Analytical Studies:
Ergostan-3-ol, (3.beta.,5.alpha.,24R)can be used as an analyte in biological and analytical studies for the determination of various natural compounds in plant tissues. This can be achieved through advanced analytical techniques such as UHPLC-ESI-MS/MS (Ultra-High Performance Liquid Chromatography-Electrospray Ionization Tandem Mass Spectrometry), which allows for the identification and quantification of trace amounts of target compounds in complex samples.

InChI:InChI=1/C28H50O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h18-26,29H,7-17H2,1-6H3/t19-,20-,21+,22+,23+,24-,25+,26+,27+,28-/m1/s1

Upstream product

• 1449-60-1 (10S)-3c-Acetoxy-10r.13c-dimethyl-17c-((1R:4R)-1.4.5-trimethyl-hexen-(2t)-yl)-(5ξH.9cH.14tH)-Δ⁷-tetradecahydro-1H-cyclopenta[a]phenanthren 
• 60-29-7 diethyl ether 
• 64-19-7 acetic acid 
• 474-70-4 (10R)-3c-Hydroxy-10r.13c-dimethyl-17c-((1R:4R)-1.4.5-trimethyl-hexen-(2t)-yl)-(9cH.14tH)-Δ^5.7-dodecahydro-1H-cyclopenta[a]phenanthren 
• 1105-11-9 (10S)-3c-Hydroxy-10r.13c-dimethyl-17c-((1R:4R)-1.4.5-trimethyl-hexen-(2t)-yl)-(5ξH.9cH.14tH)-Δ⁷-tetradecahydro-1H-cyclopenta[a]phenanthren 
• 64-17-5 ethanol 
• 601-44-5 5β-lumistan-3β-ol 
• 141-52-6 sodium ethanolate 
• 1105-11-9 5β-lumistadien-(7.22t)-ol-(3α) 
• 1449-60-1 5β-lumistadien-(7.22t)-yl-(3β)-acetate 
• 474-59-9 5α,10α-ergostanol-(3β) 
• 1449-60-1 5α.10α-ergostadien-(7.22t)-yl-(3α)-acetate 
• 128-27-8 (10S)-3t-Hydroxy-10r.13t-dimethyl-17t-((1R:4R)-1.4.5-trimethyl-hexen-(2t)-yl)-(9cH.14cH)-Δ^5.7-dodecahydro-1H-cyclopenta[a]phenanthren 
• 1105-11-9 5α.10α-ergostadien-(7.22t)-ol-(3α) 

Downstream Products

• 6424-44-8 O-Benzoyl-haliclonastanol 
• 116282-74-7 O-(3.5-dinitro-benzoyl)-campestanol 
• 677324-56-0 C₃₇H₅₆O₄ 
• 677324-57-1 C₃₈H₅₈O₄ 

Relevant articles and documents

Identification of 5α-stanols in patients with sitosterolemia and xanthomatosis: Stereochemistry of the protonolysis of steroidal organoboranes

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Novel sterol/stanol phosphorylnitroderivatives and use thereof in treating or preventing cardiovascular disease, its underlying conditions and other disorders

Sterol and stanol phosphorylnitro derivatives and their use in treating or preventing cardiovascular disease, its underlying conditions and other disorders are disclosed. The disclosed compounds include a phosphate linker, at least one moiety that releases nitric oxide (NO), and a sterol or stanol moiety. Some compounds additionally include an ascorbyl moiety to make the compound more readily soluble in aqueous and non-aqueous media.

Steroids from the Starfish Euretaster insignis: A Novel Group of Sulphated 3β,21-Dihydroxysteroids

The aqueous extracts of the starfish Euretaster insignis contain two groups of sterol sulphates.The more polar compounds are sulphated 3β,21-dihydroxysteroids; after solvolysis to remove the sulphate groups they were identified as (20R)-24-methylenecholestane-3β,21-diol (3a) (major), (20R)-24-methylenecholest-5-ene-3β,21-diol (3b) (minor), (20R,22E)-methylcholest-22-ene-3β,21-diol (4a) (major), (20R)-cholestane-3β,21-diol (1a) (minor), (20R,22E)-cholest-22-ene-3β,21-diol (2a) (minor), and (20R)-cholest-5-ene-3β,21-diol (1b) (minor).The less polar compouds are sterol sulphates wich are "normal" constituents of starfishes.Analysis of the free sterols mixture has revealed that it contains a low level of cholest-7-en-3β-ol (3percent of the total sterol mixtures) and C26, C27, C28, and C29 5α-steroidal alcohols.This finding, in contrast with previous results indicating the preponderance of Δ7-sterols in starfishes, could be related to the apparent absence of asterosaponins in this species.