474352-69-7

Basic information

• Product Name: N,3,5-trimethyl-N-phenylaniline
• Synonyms: N,3,5-trimethyl-N-phenylaniline
• CAS NO: 474352-69-7
• Molecular Weight: 211.307
• Mol File: 474352-69-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N,3,5-trimethyl-N-phenylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: N,3,5-trimethyl-N-phenylaniline(474352-69-7)
• EPA Substance Registry System: N,3,5-trimethyl-N-phenylaniline(474352-69-7)

Safety Data

• Hazardous Substances Data: 474352-69-7(Hazardous Substances Data)

Upstream product

• 556-97-8 1-chloro-3,5-dimethylbenzene 
• 100-61-8 N-methylaniline 
• 4913-13-7 3,5,N,N-tetramethylaniline 
• 88284-48-4 2-(trimethylsilyl)phenyl trifluoromethanesulfonate 

Relevant articles and documents

Solvent-free mechanochemical Buchwald-Hartwig amination of aryl chlorides without inert gas protection

A solvent-free Buchwald-Hartwig amination had been developed under high-speed ball-milling conditions, which afforded the desired products with moderate to high yields. The addition of sodium sulfate was found to be crucial for improving both the performance and the reproducibility. Comparative solvent-free stirring experiments implicated the importance of mechanical interaction for the transformation, and the inert gas was proved to be unnecessary for this amination.

Employing arynes in transition-metal-free monoarylation of aromatic tertiary amines

The highly monoselective N-arylation of aromatic tertiary amines using a transition-metal-free approach using arynes has been developed. The reaction afforded functionalized diaryl amines in moderate to excellent yield. High levels of functional group compatibility especially with halogen containing substrates, dyes and donor-acceptor systems, and high yields of products are the notable features of the present reaction.