474410-80-5

Basic information

• Product Name: 7-(4-butyrylamino-phenyl)-1-(2-fluoro-benzyl)-4-oxo-1,4-dihydro-pyrrolo[1,2-a]pyrimidine-3-carboxylic acid ethyl ester
• CAS NO: 474410-80-5
• Molecular Weight: 475.52
• Mol File: 474410-80-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-(4-butyrylamino-phenyl)-1-(2-fluoro-benzyl)-4-oxo-1,4-dihydro-pyrrolo[1,2-a]pyrimidine-3-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 7-(4-butyrylamino-phenyl)-1-(2-fluoro-benzyl)-4-oxo-1,4-dihydro-pyrrolo[1,2-a]pyrimidine-3-carboxylic acid ethyl ester(474410-80-5)
• EPA Substance Registry System: 7-(4-butyrylamino-phenyl)-1-(2-fluoro-benzyl)-4-oxo-1,4-dihydro-pyrrolo[1,2-a]pyrimidine-3-carboxylic acid ethyl ester(474410-80-5)

Safety Data

• Hazardous Substances Data: 474410-80-5(Hazardous Substances Data)

Upstream product

• 474410-70-3 1-(2-fluoro-benzyl)-7-(4-nitro-phenyl)-4-oxo-1,4-dihydro-pyrrolo[1,2-a]pyrimidine-3-carboxylic acid ethyl ester 
• 87-13-8 diethyl 2-ethoxymethylenemalonate 
• 53135-24-3 ethyl 3,4-dihydro-4-oxo-2-methylpyrimidine-5-carboxylate 
• 99-81-0 4-Nitrophenacyl bromide 
• 446-48-0 o-fluorobenzyl bromide 

Relevant articles and documents

A Novel synthesis of 2-arylpyrrolo[1,2-a]pyrimid-7-ones and their structure-activity relationships as potent GnRH receptor antagonists

In the process of developing GnRH receptor antagonists, a novel base-catalyzed cyclization of compounds 5a-b was discovered, which led to the formation of the 2-aryl pyrrolo[1,2-a]pyrimid-7-one core stuctures 6a-b. These intermediates were further modifie