4746-67-2

Basic information

• Product Name: 2,3-DIHYDRO-1H-BENZO[D]IMIDAZOLE
• Synonyms: 2,3-DIHYDRO-1H-BENZO[D]IMIDAZOLE;TETRAHYDROBENZIMIDAZOLE
• CAS NO: 4746-67-2
• Molecular Formula: C7H8N2
• Molecular Weight: 120.15
• Mol File: 4746-67-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 266.3±20.0 °C(Predicted)
• Appearance: /
• Density: 1.086±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C(protect from light)
• PKA: 6.93±0.20(Predicted)
• CAS DataBase Reference: 2,3-DIHYDRO-1H-BENZO[D]IMIDAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-DIHYDRO-1H-BENZO[D]IMIDAZOLE(4746-67-2)
• EPA Substance Registry System: 2,3-DIHYDRO-1H-BENZO[D]IMIDAZOLE(4746-67-2)

Safety Data

• Hazardous Substances Data: 4746-67-2(Hazardous Substances Data)

Usage

General Description

2,3-Dihydro-1H-benzo[d]imidazole is a chemical compound with the molecular formula C7H8N2. It is a bicyclic organic compound that contains a benzimidazole ring system. 2,3-DIHYDRO-1H-BENZO[D]IMIDAZOLE has been used in the synthesis of various pharmaceuticals and other organic compounds. It has also shown potential biological activity and has been studied for its potential use in medicinal applications. Additionally, 2,3-dihydro-1H-benzo[d]imidazole may have other industrial applications due to its unique chemical structure and properties.

Upstream product

• 583-39-1 2,3-dihydrobenzimidazol-2-thione 
• 95-54-5 1,2-diamino-benzene 
• 1355363-17-5 N-methylene1,2-phenylenediamine 
• 18227-18-4 benzimidazole hydrochloride 

Downstream Products

• 18773-95-0 1-acetylbenzimidazole 
• 51-17-2 benzoimidazole 

Relevant articles and documents

Synthesis of N-heterocyclic carbene boranes via silver N-heterocyclic carbene complexes

The reaction of N-heterocyclic carbene (NHC) complexes of silver with BH3 or BEt3 was investigated. On treatment of IiPr·AgCl (1-AgCl) (IiPr = 1,3-diisopropylimidazol-2-ylidene) with two equivalents of NaBH

Inhibitors of the salicylate synthase (Mbti) from Mycobacterium tuberculosis discovered by high-throughput screening

A simple steady-state kinetic high-throughput assay was developed for the salicylate synthase MbtI from Mycobacterium tuberculosis, which catalyzes the first committed step of mycobactin biosynthesis. The mycobactins are small-molecule iron chelators produced by M. tuberculosis, and their biosynthesis has been identified as a promising target for the development of new antitubercular agents. The assay was miniaturized to a 384-well plate format and high-throughput screening was performed at the National Screening Laboratory for the Regional Centers of Excellence in Biodefense and Emerging Infectious Diseases (NSRB). Three classes of compounds were identified comprising the benzisothiazolones (class I), diarylsulfones (class II), and benzimidazole-2-thiones (class III). Each of these compound series was further pursued to investigate their biochemical mechanism and structure-activity relationships. Benzimidazole-2-thione 4 emerged as the most promising inhibitor owing to its potent reversible inhibition.