474645-92-6Relevant articles and documents
SYNTHESIS OF IMIDE COMPOUNDS
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Page/Page column 11-13; 17-18, (2008/12/05)
The invention relates to a process for the production of an imide (1) (2) (3) via the enantioselective addition of an amine (2) to an alkene (3) wherein Y is OR, wherein R is alkyl or Bn, said process comprising: incubating Pd(OTf)2 with a phos
Asymmetric synthesis of the cholesteryl ester transfer protein inhibitor torcetrapib
Damon, David B.,Dugger, Robert W.,Hubbs, Stephen E.,Scott, Jill M.,Scott, Robert W.
, p. 472 - 480 (2012/12/22)
Previously our group reported synthetic efforts used to synthesize kilogram quantities of the cholesteryl ester transfer protein (CETP) inhibitor torcetrapib, 1, via a mid-stage resolution. This account describes research conducted to develop an asymmetri
Method for producing (R) -3- [4- (trifluoromethyl) phenylamino] -pentanoic acid amide derivative
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Page 18, (2010/02/08)
The present invention provides a method for easily producing an (R)-3-[4-(trifluoromethyl)phenylamino]-pentanoic acid amide derivative useful for an intermediate for pharmaceutical products, particularly an inhibitor of a cholesteryl ester transfer protei
