475110-08-8Relevant articles and documents
Synthesis of novel chiral macrolides and their antifungal activity
Gao, Ming Zhang,Gao, Jian,Xu, Zun Le,Zingaro, Ralph A.
, p. 5001 - 5003 (2002)
Nineteen chiral macrocyclic diamide-diester ligands were synthesized using a three step reaction. The synthesis utilized the condensation of dicarbonyl dichlorides with chiral 2-aminoethanol derivatives. The reaction was catalyzed in a dual catalyst system. Some of the compounds were found to display antifungal activity.