475209-02-0

Basic information

• Product Name: p-nonylbenzyl alcohol
• Synonyms: p-nonylbenzyl alcohol
• CAS NO: 475209-02-0
• Molecular Weight: 234.382
• Mol File: 475209-02-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: p-nonylbenzyl alcohol(CAS DataBase Reference)
• NIST Chemistry Reference: p-nonylbenzyl alcohol(475209-02-0)
• EPA Substance Registry System: p-nonylbenzyl alcohol(475209-02-0)

Safety Data

• Hazardous Substances Data: 475209-02-0(Hazardous Substances Data)

Upstream product

• 42036-78-2 n-octyltriphenylphosphoniumbromide 
• 69655-95-4 p-nonylbenzyl bromide 
• 70972-98-4 4-(n-nonyl)benzaldehyde 
• 140-11-4 Benzyl acetate 
• 764-85-2 Nonanoyl chloride 
• 827028-06-8 4-non-1-ynyl-benzoic acid ethyl ester 
• 51934-41-9 4-iodobenzoic acid ethyl ester 
• 3452-09-3 1-nonyne 
• 475208-92-5 4-Nonyl-benzoic acid ethyl ester 
• 38289-46-2 4-n-Nonylbenzoic acid 

Downstream Products

• 70972-98-4 4-(n-nonyl)benzaldehyde 
• 162360-11-4 2-Acetamido-1,3-diacetoxy-2-(4-nonylphenylmethyl)propane 
• 296282-47-8 2-acetylamino-2-(4-nonyl-benzyl)-malonic acid diethyl ester 
• 1026921-25-4 N-[1,1-bis-hydroxymethyl-2-(4-nonyl-phenyl)-ethyl]-acetamide 
• 571206-48-9 1-iodomethyl-4-nonyl-benzene 

Relevant articles and documents

Structural optimization and neurotrophic activity evaluation of neurotrophic gentiside derivatives

C14 alkyl benzoate ABG001, derived from naturally occurring gentisides, was reported to exhibit neurotrophic activity which is similar to NGF (Nerve Growth Factor). In this research, ABG001 was modified by the strategy of isosteric replacement and conformational restriction with the purpose of improving the bioactivity. The cellular neurotrophic activity of those ABG001 derivatives were evaluated, among which 3-hydroxyquinolin-2-(1H)-one A3 and 4-decylphenol ester B7 displayed much better neurotrophic activity compared with ABG001, which highlights the potential of those novel scaffolds for future neurotrophic agent development.

Alkyl phenylcarbinol polyoxyethylene ether and preparation method thereof

The application discloses an alkyl phenylcarbinol polyoxyethylene ether and a preparation method thereof, the molecular structure of the alkyl phenylcarbinol polyoxyethylene ether comprises a hydrophobic group and a hydrophilic group, the molecular structural formula is shown in the description, wherein R in the molecular formula is alkyl, and n is equal to 3-50. The alkyl phenylcarbinol polyoxyethylene ether has excellent effects of moisturizing, permeating, emulsifying, dispersing, solubilizing and washing, can be used as an emulgator, a textile assistant, a detergent, a dispersing agent, a softening agent, a petroleum demulsifier and the like, completely replaces an alkylphenol ethoxylates emulgator, and is widely applied to the industries of detergents, personal care products, textile, paper-making, petroleum, pesticides, pharmacy, printing, synthetic rubbers, waterborne emulsions, coatings, printing ink, adhesives, plastics and the like.

Development of novel EDG3 antagonists using a 3D database search and their structure-activity relationships

Sphingosine-1-phosphate (S1P) is an intracellular second messenger and an extracellular mediator through endothelial differentiation gene (EDG) receptors, which are a novel class of G-protein-coupled receptors. Although EDG has attracted much attention because of its various roles, no selective agonists or antagonists have yet been developed. This could account for the delay in clarifying the physiological roles of members of the EDG family. Because precise structural information on EDG receptors is not yet available, pharmacophore models were generated based on structural information for S1P using the rational drug design software Catalyst. Novel antagonists, 2-alkylthiazolidine-4-carboxylic acids, were retrieved from a three-dimensional database search using the pharmacophore models, and these showed activity for EDG3. On the basis of their nonphosphoric acid structure, more potent antagonists, 2-(m- or p-heptylphenyl)thiazolidine-4-carboxylic acid, were developed.