475215-88-4Relevant articles and documents
NEW CLASS OF DNA GYRASE AND/OR TOPOISOMERASE IV INHIBITORS WITH ACTIVITY AGAINST GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA
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, (2020/03/29)
The present invention relates to compounds having a structure of general formula (I), processes for their preparation, pharmaceutical compositions containing them as the active ingredient, to their use as medicaments and to their use in the manufacture of medicaments for use in the treatment of bacterial infections in humans and warm-blooded animals.
Transition metals in organic synthesis. Part 101: Convergent total synthesis of 1,6-dioxygenated carbazole alkaloids
B?rger, Carsten,Kn?lker, Hans-Joachim
, p. 6727 - 6736 (2012/09/05)
Using a palladium(II)-catalysed oxidative cyclisation as key step, we describe a highly efficient total synthesis of a series of naturally occurring 1,6-dioxygenated carbazole alkaloids: clausenine, 6-methoxymurrayanine, clausenol, clausine G, clausine I, clausine Z and methyl 1,6-dihydroxy-9H- carbazole-3-carboxylate.
Transition metals in organic synthesis, Part 85.1 A general approach to 1,6-dioxygenated carbazole alkaloids - first total synthesis of clausine G, clausine I, and clausine Z
B?rger, Carsten,Kn?lker, Hans-Joachim
body text, p. 1698 - 1702 (2009/05/07)
Using the palladium-catalyzed construction of the carbazole framework, a highly efficient route to 1,6-dioxygenated carbazole alkaloids has been developed and applied to the total synthesis of clausenine, 6- methoxymurrayanine, clausenol, clausine G, clausine I, and clausine Z. The three latter natural products have been synthesized for the first time. Thieme Stuttgart.