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475272-67-4

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475272-67-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 475272-67-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,5,2,7 and 2 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 475272-67:
(8*4)+(7*7)+(6*5)+(5*2)+(4*7)+(3*2)+(2*6)+(1*7)=174
174 % 10 = 4
So 475272-67-4 is a valid CAS Registry Number.

475272-67-4Relevant articles and documents

Design and application of an α-helix-mimetic scaffold based on an oligoamide-foldamer strategy: Antagonism of the Bak BH3/Bcl-xL complex

Ernst, Justin T.,Becerril, Jorge,Park, Hyung Soon,Yin, Hang,Hamilton, Andrew D.

, p. 535 - 539 (2003)

The prevention of cell death by the antiapoptotic protein Bcl-xL has been linked to a number of cancers. Bcl-xl binds to the BH3 domain of the proapoptotic protein Bak, thus preventing programmed cell death. A competitive assay and docking studies have shown that the polyamide scaffold 1, which was synthesized based on a rational structure-based design, interferes with the Bak BH3/Bcl-xl complexation.

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