475288-42-7 Usage
Description
(E)-3-Bromo-2-tert-butoxycarbonylamino-but-2-enoic acid methyl ester is a synthetic organic compound with the molecular formula C11H17BrNO4. It is a methyl ester derivative of (E)-3-bromo-2-tert-butoxycarbonylamino-but-2-enoic acid, characterized by its versatile reactivity and structural properties. (E)-3-Bromo-2-tert-butoxycarbonylamino-but-2-enoic acid methyl ester is widely utilized in organic synthesis and pharmaceutical research, serving as a key building block in the creation of various biologically active molecules.
Uses
Used in Pharmaceutical Research:
(E)-3-Bromo-2-tert-butoxycarbonylamino-but-2-enoic acid methyl ester is used as a building block for the synthesis of biologically active compounds in pharmaceutical research. Its unique structural properties and reactivity make it a valuable component in the development of new drugs and pharmaceuticals.
Used in Organic Synthesis:
In the field of organic synthesis, (E)-3-Bromo-2-tert-butoxycarbonylamino-but-2-enoic acid methyl ester is employed as a versatile intermediate. Its ability to react with a range of other compounds allows for the creation of diverse chemical products, contributing to the advancement of organic chemistry.
Used in Drug Development:
(E)-3-Bromo-2-tert-butoxycarbonylamino-but-2-enoic acid methyl ester is used as a crucial component in drug development. Its incorporation into the molecular structure of potential drugs can enhance their efficacy, selectivity, and pharmacokinetic properties, ultimately leading to the creation of more effective therapeutic agents.
Used in Chemical Research:
In chemical research, (E)-3-Bromo-2-tert-butoxycarbonylamino-but-2-enoic acid methyl ester serves as a model compound for studying various reaction mechanisms and exploring new synthetic pathways. Its unique properties make it an ideal candidate for investigating novel chemical transformations and understanding the underlying principles of organic chemistry.
Overall, (E)-3-Bromo-2-tert-butoxycarbonylamino-but-2-enoic acid methyl ester is a versatile and valuable compound in the fields of pharmaceutical research, organic synthesis, drug development, and chemical research. Its diverse applications and potential for further exploration make it a promising candidate for future scientific advancements.
Check Digit Verification of cas no
The CAS Registry Mumber 475288-42-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,5,2,8 and 8 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 475288-42:
(8*4)+(7*7)+(6*5)+(5*2)+(4*8)+(3*8)+(2*4)+(1*2)=187
187 % 10 = 7
So 475288-42-7 is a valid CAS Registry Number.
475288-42-7Relevant articles and documents
High yielding synthesis of N-ethyl dehydroamino acids
Monteiro, Luís S.,Suárez, Ana S.
, p. 1643 - 1652 (2013/01/14)
Recently we reported the use of Asequence of alkylation and dehydration methodologies to obtain N-ethyl-α, β-dehydroamino acid derivatives. The application of this N-Alkylation procedure to several methyl esters of β,β-dibromo and β-bromo, β-substituted dehydroamino acids protected with standard amine protecting groups was subsequently reported. The corresponding N-ethyl, β-bromo dehydroamino acid derivatives were obtained in fair to high yields and some were used as substrates in Suzuki cross-coupling reactions to give N-ethyl, β,β-disubstituted dehydroalanine derivatives. Herein, we further explore N-ethylation of β-halo dehydroamino acid derivatives using triethyloxonium tetrafluoroborate as alkylating agent, but substituting N,N-diisopropylethylamine for potassium tert-butoxide as auxiliary base. In these conditions, for all β-halo dehydroamino acid derivatives, reactions were complete and the N-ethylated derivative could be isolated in high yield. This method was also applied for N-ethylation of non-halogenated dehydroamino acids. Again, with all compounds the reactions were complete and the N-ethyl dehydroamino acid derivatives could be isolated in high yields. Some of these N-ethyl dehydroamino acid methyl ester derivatives were converted in high yields to their corresponding acids and coupled to an amino acid methyl ester to give N-ethyl dehydrodipeptide derivatives in good yields. Thus, this method constitutes Ageneral procedure for high yielding synthesis of N-ethylated dehydroamino acids, which can be further applied in peptide synthesis.
