475977-79-8 Usage
General Description
2-(2,4-Dinitrobenzylthio)-1H-benzo[d]imidazole is a chemical compound with the molecular formula C14H10N4O4S. It is a benzimidazole derivative with a dinitrobenzene group and a thiol group attached to it. 2-(2,4-DINITROBENZYLTHIO)-1H-BENZO[D]IMIDAZOLE has been studied for its potential use as a fluorescent label for protein imaging and as a photosensitizer for photodynamic therapy. Additionally, it has been investigated for its biological activities, including anti-tumor and anti-inflammatory properties. Due to its unique structure and potential applications, 2-(2,4-Dinitrobenzylthio)-1H-benzo[d]imidazole is of interest in the fields of medicine and biochemistry, with ongoing research to explore its potential uses and effects.
Check Digit Verification of cas no
The CAS Registry Mumber 475977-79-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,5,9,7 and 7 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 475977-79:
(8*4)+(7*7)+(6*5)+(5*9)+(4*7)+(3*7)+(2*7)+(1*9)=228
228 % 10 = 8
So 475977-79-8 is a valid CAS Registry Number.
InChI:InChI=1/C14H10N4O4S/c19-17(20)10-6-5-9(13(7-10)18(21)22)8-23-14-15-11-3-1-2-4-12(11)16-14/h1-7H,8H2,(H,15,16)
475977-79-8Relevant articles and documents
Synthesis and preliminary evaluation of benzimidazole derivatives as antimicrobial agents
Klimesova, Vera,Koci, Jan,Pour, Milan,Stachel, Jiri,Waisser, Karel,Kaustova, Jarmila
, p. 409 - 418 (2007/10/03)
A series of 2-alkylsulphanylbenzimidazoles was synthesised and the compounds were evaluated for their in vitro antimicrobial activity. The structures of the compounds were confirmed by 1H-NMR and IR data, and their purity by elemental analysis. Antimycobacterial activities against Mycobacterium tuberculosis and non-tuberculous mycobacteria as well as antifungal activities against Candida albicans, Candida tropicalis, Candida krusei, Candida glabrata, Trichosporon beigelii, Trichophyton mentagrophytes and Aspergillus fumigatus were expressed as the corresponding MIC values. The substances exhibited appreciable antimycobacterial activity, in particular, against non-tuberculous mycobacteria. The activity of the most active compound in the set, 3,5-dinitro derivative 4t, exceeded that of the standard isoniazide against M. kansasii and M. avium. The antifungal activities of the compounds were relatively low. A weak antifungal effect was observed against the dermatophyte Trichophyton mentagrophytes. None of the compounds showed significant inhibitory activity against yeasts.
