476334-33-5 Usage
General Description
(R)-BorohomoPhe-(+)-Pinanediol-HCl is a chiral reagent with a boron atom attached to a homo-phenyl group and a pinanediol moiety, which is in the form of a hydrochloride salt. It is commonly used in organic synthesis as a chiral auxilliary for the enantioselective reduction of ketones and imines. The boron atom in the compound allows for easy manipulation of the stereochemistry in the target molecule, and the pinanediol group provides additional stereoselectivity. This reagent has found applications in the synthesis of pharmaceuticals, agrochemicals, and fine chemicals, and it has proven to be a versatile and efficient tool in asymmetric synthesis.
Check Digit Verification of cas no
The CAS Registry Mumber 476334-33-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,6,3,3 and 4 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 476334-33:
(8*4)+(7*7)+(6*6)+(5*3)+(4*3)+(3*4)+(2*3)+(1*3)=165
165 % 10 = 5
So 476334-33-5 is a valid CAS Registry Number.
476334-33-5Relevant articles and documents
P1 Phenethyl peptide boronic acid inhibitors of HCV NS3 protease
Priestley,De Lucca, Indawati,Ghavimi, Bahman,Erickson-Viitanen, Susan,Decicco, Carl P.
, p. 3199 - 3202 (2007/10/03)
A series of peptide boronic acids containing extended, hydrophobic P1 residues was prepared to probe the shallow, hydrophobic S1 region of HCV NS3 protease. The p-trifluoromethylphenethyl P1 substituent was identified as optimal with respect to inhibitor potency for NS3 and selectivity against elastase and chymotrypsin.