476472-02-3

Basic information

• Product Name: 1-(6-METHYLPYRIDYL)-2-QUINOLIN-4-YL ETHANONE
• Synonyms: 1-(6-METHYLPYRIDYL)-2-QUINOLIN-4-YL ETHANONE;1-(6-Methylpyridin-2-yl)-2-(quinolin-4-yl)ethanone
• CAS NO: 476472-02-3
• Molecular Formula: C₁₇H₁₄N₂O
• Molecular Weight: 262.31
• Mol File: 476472-02-3.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 449.9°C at 760 mmHg
• Flash Point: 225.7°C
• Appearance: /
• Density: 1.2g/cm³
• Vapor Pressure: 2.75E-08mmHg at 25°C
• Refractive Index: 1.649
• CAS DataBase Reference: 1-(6-METHYLPYRIDYL)-2-QUINOLIN-4-YL ETHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(6-METHYLPYRIDYL)-2-QUINOLIN-4-YL ETHANONE(476472-02-3)
• EPA Substance Registry System: 1-(6-METHYLPYRIDYL)-2-QUINOLIN-4-YL ETHANONE(476472-02-3)

Safety Data

• Hazardous Substances Data: 476472-02-3(Hazardous Substances Data)

Usage

Molecular Structure

Complex molecular structure

Class of Compounds

Quinolones and derivatives

Usage

Primarily used for research purposes

Presence in Everyday Products

Not commonly found

Chemical Properties

Being explored

Potential Applications

Being explored

Further Research

Needed to fully understand potential uses and effects

InChI:InChI=1/C17H14N2O/c1-12-5-4-8-16(19-12)17(20)11-13-9-10-18-15-7-3-2-6-14(13)15/h2-10H,11H2,1H3

Upstream product

• 491-35-0 C₆H₄NCH₂CHCCH₂ 
• 13602-11-4 6-methylpicolinic acid methyl ester 
• 4363-93-3 quinoline-4-carboxaldehyde 
• 614750-85-5 diphenyl (6-methylpyridin-2-yl)(phenylamino)methylphosphonate 
• 39640-51-2 ethyl 6-methylpyridine-2-carboxylate 
• 934-60-1 6-methyl-2-pyridinecarboxylic acid 

Downstream Products

• 607737-87-1 4-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)quinoline 

Relevant articles and documents

BENZYLAMIDE DERIVATIVES AS INHIBITORS OF TRANSFORMING GROWTH FACTOR-BETA RECEPTOR I/ALK5

The present invention relates to novel benzylamide derivatives of formula (I) to processes for the preparation of said compounds; to pharmaceutical compositions comprising said compounds and to said compounds for use in the treatment of pathological conditions or diseases that can improve by inhibition of transforming growth factor-β receptor I (TGFβRI)/ALK5, such as diseases and disorders associated to fibrotic conditions of gastrointestinal system, skin and eyes, to methods for the treatment and/or prevention of said diseases or pathological conditions and to combinations comprising said compounds and further comprising therapeutically effective amounts of other therapeutic agents useful for the treatment of said diseases or pathological conditions.

Synthesis and biological evaluation of 2-pyridyl-substituted pyrazoles and imidazoles as transforming growth factor-β type 1 receptor kinase inhibitors

A series of 2-pyridyl-substituted pyrazoles (16a-d, 17, 18, and 28a-e) and imidazoles (22 and 23) has been synthesized and evaluated for their ALK5 inhibitory activity in cell-based luciferase reporter assays. Among them, 3-(3-(6-methylpyridin-2-yl)-4-(qu

NOVEL ISOTHIAZOLE AND ISOXAZOLE COMPOUNDS AS TRANSFORMING GROWTH FACTOR (TGF) INHIBITORS

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