47672-25-3

Basic information

• Product Name: L-Phenylalanine, N-(triphenylmethyl)-
• Synonyms: Tr-Phe-OH;N-Trityl-L-phenylalanin;N-trityl-L-phenylalanine
• CAS NO: 47672-25-3
• Molecular Formula: C28H25NO2
• Molecular Weight: 407.50400
• Mol File: 47672-25-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: L-Phenylalanine, N-(triphenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: L-Phenylalanine, N-(triphenylmethyl)-(47672-25-3)
• EPA Substance Registry System: L-Phenylalanine, N-(triphenylmethyl)-(47672-25-3)

Safety Data

• Hazardous Substances Data: 47672-25-3(Hazardous Substances Data)

Usage

General Description

L-Phenylalanine, N-(triphenylmethyl)- is a chemical compound with the molecular formula C27H25NO2. It is a derivative of the essential amino acid L-phenylalanine, which plays a crucial role in protein synthesis and is important for the proper functioning of the nervous system. N-(triphenylmethyl)- is a synthetic derivative of L-phenylalanine and is commonly used in pharmaceutical research as a tool to study biological processes and design new drugs. However, the compound is not widely used in commercial products and its specific properties and applications are still being explored by researchers.

Upstream product

• 150-30-1 Phenylalanine 
• 76-83-5 trityl chloride 
• 63-91-2 L-phenylalanine 
• 5269-44-3 O-(Trimethylsilyl)phenylalanine 

Downstream Products

• 73994-87-3 (S)-benzyl 2-((S)-2-amino-3-phenylpropanamido)-4-methylpentanoate hydrochloride 
• 63649-15-0 L-phenylalanyl-L-leucine benzyl ester 
• 131941-55-4 Trt-Phe-ODhbt 
• 100841-19-8 (S)-(-)-3-Phenyl-2-triphenylmethylamino-1-propanol 
• 92466-03-0 N-trityl-phenylalanine-glycine benzyl ester 
• 92466-04-1 Trt-Phe-Leu-OBzl 
• 115731-96-9 Trt-Phe-ODpm 
• 92466-16-5 N-trityl-phenylalanine succinimide ester 
• 5879-43-6 (+/-)-N-Trityl-phenylalanin-<2-methylmercaptoaethylester> 
• 872719-69-2 Ac-[D-Tyr⁴⁶,D-Trp⁴⁷,Thr⁴⁹,azaGly⁵¹,Arg(Me)⁵³]metastin(46-54) 
• 872718-97-3 [D-Tyr⁴⁶,D-Pya⁽⁴⁾⁴⁷,Ala⁴⁸,azaGly⁵¹,Arg(Me)⁵³,Trp⁵⁴]metastin(46-54) 
• 872719-29-4 [D-Tyr⁴⁶,D-Pya⁽⁴⁾⁴⁷,Hyp⁴⁹,azaGly⁵¹,Arg(Me)⁵³,Trp⁵⁴]metastin(46-54) 
• 872719-30-7 [D-Tyr⁴⁶,D-Pya⁽⁴⁾⁴⁷,Pro⁴⁹,azaGly⁵¹,Arg(Me)⁵³,Trp⁵⁴]metastin(46-54) 
• 872719-31-8 [D-Tyr⁴⁶,D-Pya⁽⁴⁾⁴⁷,Tle⁴⁹,azaGly⁵¹,Arg(Me)⁵³,Trp⁵⁴]metastin(46-54) 

Relevant articles and documents

Hydrogen-Borrowing Alkylation of 1,2-Amino Alcohols in the Synthesis of Enantioenriched γ-Aminobutyric Acids

For the first time we have been able to employ enantiopure 1,2-amino alcohols derived from abundant amino acids in C?C bond-forming hydrogen-borrowing alkylation reactions. These reactions are facilitated by the use of the aryl ketone Ph*COMe. Racemisation of the amine stereocentre during alkylation can be prevented by the use of sub-stoichiometric base and protection of the nitrogen with a sterically hindered triphenylmethane (trityl) or benzyl group. The Ph* and trityl groups are readily cleaved in one pot to give γ-aminobutyric acid (GABA) products as their HCl salts without further purification. Both steps may be performed in sequence without isolation of the hydrogen-borrowing intermediate, removing the need for column chromatography.

N-trityl- and N-phenylfluorenyl-N-carboxyanhydrides and their use in dipeptide synthesis

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Efficient "One-Pot" Synthesis of N-Trityl Amino Acids

A sequential procedure has been developed whereby neutral amino acids 1 were tritylated via their corresponding trimethylsilyl esters 2 to afford, after mild hydrolysis, N-trityl amino acids 3 in high yields and purity.Hydroxy amino acids 4 were preferent