477-20-3

Basic information

• Product Name: homolycorine
• Synonyms: homolycorine;1-Methyl-9,10-dimethoxy-1,2,3,5aα,11bα,11cβ-hexahydro[2]benzopyrano[3,4-g]indole-7(5H)-one;9,10-Dimethoxy-1-methyllycorenan-7-one
• CAS NO: 477-20-3
• Molecular Formula: C18H21NO4
• Molecular Weight: 315.36364
• Mol File: 477-20-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 493.1°Cat760mmHg
• Flash Point: 252°C
• Appearance: /
• Density: 1.28g/cm³
• Vapor Pressure: 7.24E-10mmHg at 25°C
• Refractive Index: 1.607
• CAS DataBase Reference: homolycorine(CAS DataBase Reference)
• NIST Chemistry Reference: homolycorine(477-20-3)
• EPA Substance Registry System: homolycorine(477-20-3)

Safety Data

• Hazardous Substances Data: 477-20-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C18H21NO4/c1-19-7-6-10-4-5-13-16(17(10)19)11-8-14(21-2)15(22-3)9-12(11)18(20)23-13/h4,8-9,13,16-17H,5-7H2,1-3H3/t13-,16-,17-/m1/s1

Upstream product

• 186581-53-3 diazomethane 
• 6879-81-8 (+)-9-O-Demethylhomolycorine 
• 64-19-7 acetic acid 
• 67-66-3 chloroform 
• 7664-93-9 sulfuric acid 
• 7732-18-5 water 
• 64-17-5 ethanol 

Relevant articles and documents

Structures of 9-O-Demethylhomolycorine and 5α-Hydroxyhomolycorine. Alkaloids of Crinum defixum, C. scabrum, and C. latifolium. Assignment of Aromatic Substitution Patterns from 1H-Coupled 13C Spectra

The isolation and characterization of the major crystalline alkaloids of three Crinum species, C. defixum, C. scabrum, and C. latifolium, are reported.A new alkaloid, 5α-hydroxyhomolycorine (1) has been isolated from C. defixum.The latter plant also contains an alkaloid identified as 9-O-demethylhomolycorine which differs in physical properties from that previously reported for this compound.Evidence is provided for the structure of 9-O-demethylhomolycorine by 1H and 13C NMR studies.In the latter, the exploitation of long-range 1H coupling in the 13C spectra of lactones in this series is found to be diagnostically useful in assigning aromatic substitution patterns.A survey of the CD spectra of lactone alkaloids of the benzopyranoindole system indicates that this technique can provide useful structural information.