477-82-7 Usage
Description
11-Methoxy-5-methyl-1,3-dioxolo[4,5-b]acridin-10(5H)-one is a complex organic compound belonging to the acridine family, characterized by its unique molecular structure featuring a 1,3-dioxolo fused ring system and a 5-membered acridinone core. 11-Methoxy-5-methyl-1,3-dioxolo[4,5-b]acridin-10(5H)-one is known for its potential biological activities and applications in various fields.
Uses
Used in Pharmaceutical Industry:
11-Methoxy-5-methyl-1,3-dioxolo[4,5-b]acridin-10(5H)-one is used as a pharmaceutical compound for its potential therapeutic applications. 11-Methoxy-5-methyl-1,3-dioxolo[4,5-b]acridin-10(5H)-one's unique structure and properties make it a candidate for the development of new drugs targeting various diseases, including cancer and other conditions.
Used in Anticancer Applications:
In the field of oncology, 11-Methoxy-5-methyl-1,3-dioxolo[4,5-b]acridin-10(5H)-one is used as an anticancer agent. Its specific mode of action and target pathways may vary, but it is likely to exhibit inhibitory effects on tumor growth and progression by interacting with cellular and molecular targets within cancer cells.
Used in Drug Delivery Systems:
To enhance the bioavailability, delivery, and therapeutic outcomes of 11-Methoxy-5-methyl-1,3-dioxolo[4,5-b]acridin-10(5H)-one, it can be incorporated into various drug delivery systems. These systems may include organic and metallic nanoparticles, liposomes, or other advanced formulations designed to improve the compound's pharmacokinetics and pharmacodynamics.
Check Digit Verification of cas no
The CAS Registry Mumber 477-82-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,7 and 7 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 477-82:
(5*4)+(4*7)+(3*7)+(2*8)+(1*2)=87
87 % 10 = 7
So 477-82-7 is a valid CAS Registry Number.
InChI:InChI=1/C16H13NO4/c1-17-10-6-4-3-5-9(10)14(18)13-11(17)7-12-15(16(13)19-2)21-8-20-12/h3-7H,8H2,1-2H3
477-82-7Relevant articles and documents
The Chemistry of 2H-3,1-Benzoxazine-2,4(1H)-dione (Isatoic Anhydride). 21. A Mild Process For The Preparation of 10-Alkyl-9-acridanones And It's Application To The Synthesis of Acridone Alkaloids
Coppola, Gary M.,Schuster, Herbert F.
, p. 957 - 964 (2007/10/02)
10-Substituted-9-acridanones are readily prepared by the reaction of the corresponding isatoic anhydride with the lithium enolate of 2-cyclohexen-1-one.The initially formed product, the 1,2-dihydroacridone need not be purified but can be aromatized directly with DDQ to the desired acridone.This methodology is applicable to the synthesis of acridone natural products.Two alkaloids, 1,2,3-trimethoxy-10-methylacridone (9) and evoxanthine (10), were prepared from 4,5,6-trimethoxy-N-methylisatoic anhydride and 6-methoxy-4,5-methylenedioxy-N-methylisatoic anhydride respectively.In these trioxygenated systems, palladium-on-charcoal must be used to aromatize the penultimate intermediate.
