477244-18-1

Basic information

• Product Name: 2-(2,2-diphenylbenzo[1,3]dioxol-5-yl)-3-(2,3,4,6-tetra-O-acetyl)-β-D-glucopyranosyloxy-5,7-dihydroxy-4H-chromen-4-one
• Synonyms: 2-(2,2-diphenylbenzo[1,3]dioxol-5-yl)-3-(2,3,4,6-tetra-O-acetyl)-β-D-glucopyranosyloxy-5,7-dihydroxy-4H-chromen-4-one
• CAS NO: 477244-18-1
• Molecular Weight: 796.738
• Mol File: 477244-18-1.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 2-(2,2-diphenylbenzo[1,3]dioxol-5-yl)-3-(2,3,4,6-tetra-O-acetyl)-β-D-glucopyranosyloxy-5,7-dihydroxy-4H-chromen-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,2-diphenylbenzo[1,3]dioxol-5-yl)-3-(2,3,4,6-tetra-O-acetyl)-β-D-glucopyranosyloxy-5,7-dihydroxy-4H-chromen-4-one(477244-18-1)
• EPA Substance Registry System: 2-(2,2-diphenylbenzo[1,3]dioxol-5-yl)-3-(2,3,4,6-tetra-O-acetyl)-β-D-glucopyranosyloxy-5,7-dihydroxy-4H-chromen-4-one(477244-18-1)

Safety Data

• Hazardous Substances Data: 477244-18-1(Hazardous Substances Data)

Upstream product

• 572-09-8 2,3,4,6-tetra-O-acetyl-D-glucopyranosyl bromide 
• 357194-03-7 2-(2,2-diphenylbenzo[1,3]dioxol-5-yl)-3,5,7-trihydroxychromen-4-one 
• 604-69-3 β-D-glucose pentaacetate 
• 117-39-5 quercetol 
• 2051-90-3 Dichlorodiphenylmethane 
• 572-09-8 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide 

Downstream Products

• 1246840-48-1 5,7-dibenzyloxy-2-(2,2-diphenylbenzo[d][1,3]dioxol-5-yl)-3-β-D-(4'',6''-O-isopropylidene)glucosyl-4H-chromen-4-one 
• 22688-79-5 quercetin 3-O-β-D-glucuronopyranoside 
• 482-35-9 isoquercetin 
• 39028-59-6 3-O-(2'',3'',4'',6''-tetra-O-acetyl-β-D-glucopyranosyl)-3',4',5,7-tetrahydroxyflavonol 

Relevant articles and documents

NOVEL FLAVANONE DERIVATIVE

Provided is a novel antimicrobial agent. More specifically, provided is a novel antimicrobial agent capable of effectively acting on various resistant bacteria such as VSSA, MRSA, VISA, VRE, and VRSA. A novel flavanone derivative having a six-membered monosaccharide derivative, specifically, a glucose derivative or a galactose derivative is capable of effectively acting on the bacteria. More specifically, a compound represented by the general formula (I) is capable of effectively acting on the bacteria. (In the formula: X represents a six-membered monosaccharide derivative; and Y is substituted by a hydroxyl group.)

Design, synthesis, and biological evaluation of a novel series of quercetin diacylglucosides as potent anti-MRSA and anti-VRE agents

A series of novel quercetin diacylglucosides were designed and first synthesized by Steglich esterification on the basis of MRSA strains inhibiting natural compound A. The in vitro inhibition of different multi-drug resistant bacterial strains and Escherichia coli DNA gyrase B was investigated. In the series, compound 10h was up to 128-fold more potent against vancomycin-resistant enterococci and more effective than A, which represents a promising new candidate as a potent anti-MRSA and anti-VRE agent.

Binding interaction of quercetin-3-β-galactoside and its synthetic derivatives with SARS-CoV 3CLpro: Structure-activity relationship studies reveal salient pharmacophore features

The 3C-like protease (3CLpro) of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) is one of the most promising targets for discovery of drugs against SARS, because of its critical role in the viral life cycle. In this study,