477291-09-1

Basic information

• Product Name: 4-METHYL-2-[4-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOLE-5-CARBONYL CHLORIDE
• Synonyms: 4-METHYL-2-[4-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOLE-5-CARBONYL CHLORIDE;4-Methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-1,3-thiazole-5-carbonyl chloride;4-Methyl-2-[4-(trifluoromethyl)phenyl]thiazole-5-carbonyl chloride;4-Methyl-2-[4-(trifluoromethyl)phenyl]thiazole-5-carboxylic acid chloride
• CAS NO: 477291-09-1
• Molecular Formula: C₁₂H₇ClF₃NOS
• Molecular Weight: 305.7
• Mol File: 477291-09-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 369.4°Cat760mmHg
• Flash Point: 177.2°C
• Appearance: /
• Density: 1.431g/cm³
• Vapor Pressure: 1.19E-05mmHg at 25°C
• Refractive Index: 1.543
• CAS DataBase Reference: 4-METHYL-2-[4-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOLE-5-CARBONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHYL-2-[4-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOLE-5-CARBONYL CHLORIDE(477291-09-1)
• EPA Substance Registry System: 4-METHYL-2-[4-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOLE-5-CARBONYL CHLORIDE(477291-09-1)

Safety Data

• Hazardous Substances Data: 477291-09-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H7ClF3NOS/c1-6-9(10(13)18)19-11(17-6)7-2-4-8(5-3-7)12(14,15)16/h2-5H,1H3

Upstream product

• 144059-86-9 4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxylic acid 
• 72505-21-6 4-trifluoromethylbenzthioamide 
• 175277-03-9 4-methyl-2-[4-(trifluoromethyl)phenyl]thiazole-5-carboxylic acid ethyl ester 

Downstream Products

• 800373-88-0 C₂₇H₂₇F₃N₂O₄S 
• 343321-95-9 2-methyl-2-[4-{[(4-methyl-2-[4-trifluoromethylphenyl]-1,3-thiazol-5-ylcarbonyl)amino]methyl}phenoxy]propionic acid ethyl ester 
• 343321-97-1 N-methyl-2-methyl-2-[4-{[(4-methyl-2-[4-trifluoromethylphenyl]-1,3-thiazol-5-ylcarbonyl)amino]methyl}phenoxy]propionic acid ethyl ester 
• 1083418-45-4 4-methyl-2-(4-trifluoromethyl-phenyl)-thiazole-5-carboxylic acid [5-chloro-2-(1H-tetrazol-5-yl)-phenyl]-amide 

Relevant articles and documents

Thiazole-5-carboxamide compounds, and its preparation, and pharmaceutical composition and use thereof (by machine translation)

The invention relates to a novel 2-phenylthiazole-5-methanamide compound shown as a general formula I, a precursor, a stereo isomer and physiologically-acceptable salt thereof, a medicinal composition containing the compound, and an application of the compound as the aspect of medicine.

TETRAHYDROISOQUINOLINE DERIVATIVES AS PPAR-α ACTIVATORS

PPAR alpha activators, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-c