477870-37-4 Usage
3. Compound Type
Pyrrole derivative
4. Functional Groups:
Benzoyl group attached to nitrogen
Thienylmethyl group attached to carbonyl carbon
5. Interest in Pharmaceutical Research:
Potential biological activities as an enzyme inhibitor or antitumor agent
6. Target for:
Synthetic chemistry studies
Medicinal chemistry studies
Check Digit Verification of cas no
The CAS Registry Mumber 477870-37-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,7,8,7 and 0 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 477870-37:
(8*4)+(7*7)+(6*7)+(5*8)+(4*7)+(3*0)+(2*3)+(1*7)=204
204 % 10 = 4
So 477870-37-4 is a valid CAS Registry Number.
477870-37-4Relevant articles and documents
The discovery and initial optimisation of pyrrole-2-carboxamides as inhibitors of p38α MAP kinase
Down, Kenneth,Bamborough, Paul,Alder, Catherine,Campbell, Amanda,Christopher, John A.,Gerelle, Maria,Ludbrook, Steve,Mallett, Dave,Mellor, Geoff,Miller, David D.,Pearson, Rosannah,Ray, Keith,Solanke, Yemisi,Somers, Don
scheme or table, p. 3936 - 3940 (2010/08/19)
A novel pyrrole-2-carboxamide series of p38α inhibitors, discovered through the application of virtual screening, is presented. Following evaluation of activity, selectivity and developability properties of commercially available analogues, a synthesis program enabled rapid assessment of the series' suitability for further lead optimisation studies.
