478035-99-3

Basic information

• Product Name: Pyrazine, 2-chloro-5-(2,4-dimethoxyphenyl)-3,6-diethyl-
• CAS NO: 478035-99-3
• Molecular Formula: C16H19ClN2O2
• Molecular Weight: 306.792
• Mol File: 478035-99-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Pyrazine, 2-chloro-5-(2,4-dimethoxyphenyl)-3,6-diethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrazine, 2-chloro-5-(2,4-dimethoxyphenyl)-3,6-diethyl-(478035-99-3)
• EPA Substance Registry System: Pyrazine, 2-chloro-5-(2,4-dimethoxyphenyl)-3,6-diethyl-(478035-99-3)

Safety Data

• Hazardous Substances Data: 478035-99-3(Hazardous Substances Data)

Upstream product

• 72875-84-4 2,5-dichloro-3,6-diethylpyrazine 4-oxide 
• 5625-42-3 3,6-diethyl-piperazine-2,5-dione 

Downstream Products

• 355835-28-8 2-sec-butylsulfanyl-5-(2,4-dimethoxy-phenyl)-3,6-diethyl-pyrazine 
• 478035-73-3 2-(2,4-Dimethoxy-phenyl)-3,6-diethyl-5-(5-fluoro-2-methoxy-phenyl)-pyrazine 

Relevant articles and documents

2,5-diarylpyrazines, 2,5-diarylpyridines and 2,5-diarylpyrimidines

Diarylpyrazine, diarylpyridine, and diarylpyrimidine compounds that act as selective modulators of CRF 1 receptors are provided. These compounds are useful in the treatment of a number of CNS and periphereal disorders, particularly stress, anxiety, depression, cardiovascular disorders, and eating disorders. Methods of treatment of such disorders and well as packaged pharmaceutical compositions are also provided. Compounds of Formula I are also useful as probes for the localization of CRF receptors and as standards in assays for CRF receptor binding. Methods of using the compounds in receptor localization studies are given.