478040-42-5

Basic information

• Product Name: 2-(4-fluorophenyl)-6-iodo-8-methylimidazo[1,2-a]pyridine
• Synonyms: 2-(4-fluorophenyl)-6-iodo-8-methylimidazo[1,2-a]pyridine
• CAS NO: 478040-42-5
• Molecular Weight: 352.15
• Mol File: 478040-42-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-fluorophenyl)-6-iodo-8-methylimidazo[1,2-a]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-fluorophenyl)-6-iodo-8-methylimidazo[1,2-a]pyridine(478040-42-5)
• EPA Substance Registry System: 2-(4-fluorophenyl)-6-iodo-8-methylimidazo[1,2-a]pyridine(478040-42-5)

Safety Data

• Hazardous Substances Data: 478040-42-5(Hazardous Substances Data)

Upstream product

• 403-29-2 2-bromo-4'-fluoroacetophenone 
• 166266-19-9 2-amino-3-methyl-5-iodopyridine 

Relevant articles and documents

Convenient synthesis of alkenyl-, alkynyl-, and allenyl-substituted imidazo[1,2-a]pyridines via palladium-catalyzed cross-coupling reactions

A systematic study on the Stille and Sonogashira cross-coupling of iodinated imidazo[1,2-a]pyridines was performed, permitting the preparation of various vinyl-, ethynyl-, and allenyl-substituted derivatives. These methods are particularly valuable, given their experimental simplicity and high degree of flexibility with regard to functional groups that can be introduced in positions 3, 6, or 8 of the imidazo[1,2-a]-pyridine core. Effects concerning different substitution positions and the nature of the 2-substituent under various reaction conditions are reported in detail for the above types of unsaturated groups introduced.