478040-59-4 Usage
General Description
6-IODO-IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID is a chemical compound with the molecular formula C8H5IN2O2. It is a derivative of imidazo[1,2-a]pyridine and carboxylic acid, with an additional iodine atom attached to the imidazole ring. 6-IODO-IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID has potential applications in pharmaceutical research and drug development, as it may have biological activity that could be useful for medicinal purposes. It is important to handle this compound with caution and follow proper safety protocols, as iodine-containing substances can be hazardous if not handled properly. Further research is necessary to fully understand the properties and potential uses of 6-IODO-IMIDAZO[1,2-A]PYRIDINE-2-CARBOXYLIC ACID.
Check Digit Verification of cas no
The CAS Registry Mumber 478040-59-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,7,8,0,4 and 0 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 478040-59:
(8*4)+(7*7)+(6*8)+(5*0)+(4*4)+(3*0)+(2*5)+(1*9)=164
164 % 10 = 4
So 478040-59-4 is a valid CAS Registry Number.
478040-59-4Relevant articles and documents
Synthesis, molecular docking and anti-mycobacterial evaluation of new imidazo[1,2-a]pyridine-2-carboxamide derivatives
Jose, Gilish,Kumara, T.H. Suresha,Nagendrappa, Gopalpur,Sowmya,Sriram, Dharmarajan,Yogeeswari, Perumal,Sridevi, Jonnalagadda Padma,Row, Tayur N. Guru,Hosamani, Amar A.,Sujan Ganapathy,Chandrika,Narendra
, p. 616 - 627 (2015)
New anti-tubercular agents, imidazo[1,2-a]pyridine-2-carboxamide derivatives (5a-q) have been designed and synthesized. The structural considerations of the designed molecules were further supported by the docking study with a long-chain enoyl-acyl carrier protein reductase (InhA). The chemical structures of the new compounds were characterized by IR, 1H NMR, 13C NMR, HRMS and elemental analysis. In addition, single crystal X-ray diffraction has also been recorded for compound 5f. Compounds were evaluated in vitro against Mycobacterium tuberculosis H37Rv, and cytotoxicity against HEK-293T cell line. Amongst the tested compounds 5j, 5l and 5q were emerged as good anti-tubercular agents with low cytotoxicity. The structure-anti TB activity relationship of these derivatives was explained by molecular docking.
