4787-76-2

Basic information

• Product Name: Pyrrolidine, 1-(2-Methoxyphenyl)-
• Synonyms: Pyrrolidine, 1-(2-Methoxyphenyl)-;1-(2-methoxyphenyl)Pyrrolidine
• CAS NO: 4787-76-2
• Molecular Formula: C₁₁H₁₅NO
• Molecular Weight: 177.2429
• Mol File: 4787-76-2.mol
• Article Data: 21

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Pyrrolidine, 1-(2-Methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrrolidine, 1-(2-Methoxyphenyl)-(4787-76-2)
• EPA Substance Registry System: Pyrrolidine, 1-(2-Methoxyphenyl)-(4787-76-2)

Safety Data

• Hazardous Substances Data: 4787-76-2(Hazardous Substances Data)

Usage

General Description

Pyrrolidine, 1-(2-methoxyphenyl)-, also known as 2-MeO-PPP, is a synthetic designer drug that acts as a stimulant and entactogen. It belongs to the chemical class of substituted amphetamines and is closely related to the stimulant drug MDPV. 2-MeO-PPP has been reported to produce effects such as increased energy, euphoria, and enhanced sensory perception. It has also been associated with negative side effects such as insomnia, anxiety, and paranoia. The chemical structure of 2-MeO-PPP allows it to interact with dopamine and norepinephrine receptors in the brain, which contributes to its stimulant effects. Due to its potential for abuse and harmful effects, it is considered a controlled substance in many countries.

Upstream product

• 110-52-1 1,4-dibromo-butane 
• 90-04-0 2-methoxy-phenylamine 
• 123-75-1 pyrrolidine 
• 91-16-7 1,2-dimethoxybenzene 
• 201230-82-2 carbon monoxide 
• 15258-47-6 2-methoxy-N-allylaniline 
• 638-37-9 butanedial 
• 766-51-8 2-Chloroanisole 
• 578-57-4 2-bromoanisole 
• 529-28-2 4-iodoanisol 
• 3425-23-8 2-methoxybenzenediazonium chloride 
• 629-03-8 1 ,6-dibromohexane 
• 62-53-3 aniline 
• 23196-06-7 1-(2-methoxyphenyl)pyrrolidin-2-one 

Downstream Products

• 4787-77-3 2-(pyrrolidin-1-yl)phenol 
• 101264-86-2 dimethyl-carbamic acid-(2-pyrrolidino-phenyl ester) 
• 109366-12-3 1-(2-dimethylcarbamoyloxy-phenyl)-1-methyl-pyrrolidinium; iodide 

Relevant articles and documents

Dehydrogenation/(3+2) Cycloaddition of Saturated Aza-Heterocycles via Merging Organic Photoredox and Lewis Acid Catalysis

Herein, we report a photoinduced dehydrogenation/(3+2) cycloaddition reaction by merging organic photoredox and Lewis acid catalysis, providing a straightforward and efficient approach for directly installing a benzofuran skeleton on the saturated aza-heterocycles. In this protocol, we also describe a novel organic photocatalyst (t-Bu-DCQ) with the advantages of a wider redox potential, easy synthesis, and a low price. Furthermore, the stepwise activation mechanism of dual C(sp3)-H bonds was demonstrated by a series of experimental and computational studies.

Tropane alkaloid compounds and method of manufacturing using sequential oxidation reactions

The present invention relates to a tropane alkaloid compound sequentially using an oxidative Mannich ring reaction and a method for producing the same. The present invention provides a tropane alkaloid compound having a structure of chemical formula 1 in

Utilization of Cyclic Amides as Masked Aldehyde Equivalents in Reductive Amination Reactions

An operationally simple protocol has been discovered that couples primary or secondary amines with N-aryl-substituted lactams to deliver differentiated diamines in moderate to high yields. The process allows for the partial reduction of a lactam in the presence of Cp2ZrHCl (Schwartz's reagent), followed by a reductive amination between the resulting hemiaminal and primary or secondary amine. These reactions can be telescoped in a one-pot fashion to significantly simplify the operation. The scope of amines and substituted lactams of various ring sizes was demonstrated through the formation of a range of differentiated diamine products. Furthermore, this methodology was expanded to include N-aryl pyrrolidinone substrates with an enantiopure ester group at the 5-position, and α-amino piperidinones were prepared with complete retention of stereochemical information. The development of this chemistry has enabled the consideration of lactams as useful synthons.