479213-87-1Relevant articles and documents
Synthesis of quinazoline based chiral ligands and application in the enantioselective addition of phenylacetylene to aldehydes
Karakaya, Idris,Karabuga, Semistan,Altundas, Ramazan,Ulukanli, Sabri
, p. 8385 - 8388 (2014)
Five novel 4-phenylquinazolinols were synthesised in three steps. Their application as ligands in the titanium tetraisopropoxide promoted catalytic enantioselective addition of phenylacetylene to a variety of aldehydes gave propargylic alcohols. Under the
Catalytic claisen rearrangement by intercepting ketenimines with propargylic alcohols: A strategy to generate and transform ketenimines from radicals
Yan, Xuyang,Liu, Hongchi,Wei, Shenquan,Huang, Hanmin
supporting information, p. 6794 - 6798 (2020/09/15)
An efficient strategy for facilitating the cross-coupling of two radicals has been established via the coordination of a radical with a metal catalyst. This strategy provides a remarkable ability to harness the reactivity of nitrile-containing azoalkanes and enables a novel cascade reaction with nitrile-containing azoalkanes and propargylic alcohols to be established. By using this reaction, a range of acetylenic and allenic amides were obtained that provides a versatile platform for further derivatizations.
Palladium-catalyzed nucleophilic substitution of propargylic carbonates and meldrum's acid derivatives
Ambrogio, Ilaria,Cacchi, Sandro,Fabrizi, Giancarlo,Goggiamani, Antonella,Iazzetti, Antonia
, p. 3147 - 3151 (2015/05/13)
The palladium-catalyzed reaction of propargylic carbonates with Meldrum's acid derivatives proceeds smoothly in the presence of Pd(OAc)2 and P(2-furyl)3 in THF at 80 °C to give substitution products. The substitution products can be
