479664-04-5Relevant articles and documents
New renin inhibitors with pseudodipeptidic units in P1-P 1′ and P2′-P3′ positions
Paruszewski, Ryszard,Jaworski, Pawel,Winiecka, Iwona,Tautt, Jadwiga,Dudkiewicz, Jadwiga
, p. 850 - 853 (2002)
A series of four new potential renin inhibitors has been synthesized. The structure of the compounds was designed in such a way as to produce agents resistant to enzymatic degradation, metabolically stable, possibly potent and with improved oral absorptio