479681-20-4

Basic information

• Product Name: 2,5-Piperazinedione, 1-[(4-methoxyphenyl)methyl]-3-(1-methylethyl)-, (3S)-
• CAS NO: 479681-20-4
• Molecular Formula: C15H20N2O3
• Molecular Weight: 276.335
• Mol File: 479681-20-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2,5-Piperazinedione, 1-[(4-methoxyphenyl)methyl]-3-(1-methylethyl)-, (3S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-Piperazinedione, 1-[(4-methoxyphenyl)methyl]-3-(1-methylethyl)-, (3S)-(479681-20-4)
• EPA Substance Registry System: 2,5-Piperazinedione, 1-[(4-methoxyphenyl)methyl]-3-(1-methylethyl)-, (3S)-(479681-20-4)

Safety Data

• Hazardous Substances Data: 479681-20-4(Hazardous Substances Data)

Upstream product

• 2393-23-9 4-methoxy-benzylamine 
• 169701-39-7 (S)-N-(bromoacetyl)valine methyl ester 
• 4070-48-8 L-Valine methyl ester 
• 1492-06-4 methyl (S)-2-(2-chloroacetylamino)-2,3-dimethylbutanoate 
• 824-94-2 p-methoxybenzyl chloride 
• 16944-60-8 (2S)-isopropylpiperazine-3,6-dione 
• 1149-26-4 (S)-N-(benzyloxycarbonyl)valine 
• 60857-16-1 N-(4-methoxybenzyl)glycine ethyl ester 

Downstream Products

• 938055-37-9 (S)-N⁽¹⁾-(p-methoxybenzyl)-N⁽⁴⁾-methyl-3-isopropylpiperazine-2,5-dione 
• 479681-34-0 C₂₂H₂₆N₂O₃C₂₂H₂₆N₂O₃C₈H₆ 
• 264236-26-2 (6S)-1-(o-azidobenzoyl)-6-iso-propylpiperazine-2,5-dione 
• 946414-49-9 (S)-N⁽¹⁾-p-methoxybenzyl-3-iso-propyl-5-methoxy-3,6-dihydropyrazine-2-one 
• 479681-27-1 (S)-4-Benzyl-3-isopropyl-1-(4-methoxy-benzyl)-piperazine-2,5-dione 
• 799783-35-0 (3S)-4-(o-azidobenzoyl)-1-p-methoxybenzyl-3-isopropylpiperazine-2,5-dione 

Relevant articles and documents

INHIBITORS OF THE BCL6 BTB DOMAIN PROTEIN-PROTEIN INTERACTION AND USES THEREOF

The present application relates to compounds of Formula I (I) or pharmaceutically acceptable salts, solvates and/or prodrugs thereof, to compositions comprising these compounds or pharmaceutically acceptable salts, solvates and/or prodrugs thereof, and various uses in the treatment of diseases, disorders or conditions that are treatable by inhibiting interactions with BCL6 BTB, such as cancer.

Influence of N(2)-substitution in the alkylation of (4S)-alkyl-2,4-dihydro- 1H-pyrazino[2,1-b]quinazoline-3,6-diones

1-Alkylation of O(3)-lactim, N(11)-azaenolate dilithium species derived from N(2)-H compounds 1a and 1b and the lithium azaenolates derived from the N(2)-phenyl and N(2)-(1-arylethyl) substituted compounds 2, 3 and 4 is studied. In 1 the trans-diastereose