4797-17-5 Usage
Description
(2-nitro-phenylcarbamoyl)-amidophosphoryl chloride is a chemical compound with the molecular formula C7H7ClN2O5P. It is a derivative of carbamoyl and phosphoryl chloride, and contains a nitro group attached to a phenyl ring. (2-nitro-phenylcarbamoyl)-amidophosphoryl chloride is known for its ability to readily react with nucleophiles and form covalent bonds with other compounds, making it a versatile and useful chemical in the laboratory.
Uses
Used in Organic Synthesis:
(2-nitro-phenylcarbamoyl)-amidophosphoryl chloride is used as a building block in the synthesis of various organic compounds. Its reactivity and functional groups make it a valuable component in creating new molecules with specific properties.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (2-nitro-phenylcarbamoyl)-amidophosphoryl chloride is used as a key intermediate in the development of new drugs. Its ability to form covalent bonds with other compounds allows researchers to create novel pharmaceuticals with potential therapeutic applications.
Used in Chemical Research:
(2-nitro-phenylcarbamoyl)-amidophosphoryl chloride is also utilized in chemical research to study the properties and reactions of various compounds. Its reactivity with nucleophiles provides valuable insights into the behavior of different chemical species and contributes to the advancement of chemical knowledge.
Check Digit Verification of cas no
The CAS Registry Mumber 4797-17-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,7,9 and 7 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 4797-17:
(6*4)+(5*7)+(4*9)+(3*7)+(2*1)+(1*7)=125
125 % 10 = 5
So 4797-17-5 is a valid CAS Registry Number.
4797-17-5Relevant articles and documents
Synthesis, crystal structure, biological evaluation, electronic aspects of hydrogen bonds, and QSAR studies of some new N-(substituted phenylurea) diazaphosphore derivatives as anticancer agents
Dorosti, Niloufar,Delfan, Bahram,Gholivand, Khodayar,Ebrahimi Valmoozi, Ali Asghar
, p. 769 - 789 (2016/03/08)
A new series of 2-[N-(R-phenylureido)]-1,3,2-diazaphosphore-2-oxide derivatives (R = CH3, F, NO2, CN) were synthesized and characterized by 31P, 1H, 13C NMR and FT-IR spectral techniques. All the compounds were evaluated for their antibacterial activity against some Gram-positive, Gram-negative strains of bacteria, as well as for their cytotoxic effects on MCF-7, MDA-MB-231, PC-3, HeLa, and K562 human cell lines. In vitro activity results exhibited an important role for six-membered diaza ring in both assays as well as high effect of meta-methyl and ortho-fluoro substitutes on the aromatic ring against the studied human cell lines and B. subtilis bacteria, respectively. To understand the correlation between the anticancer activity and physicochemical properties of the synthesized compounds, the QSAR studies were carried out. Further, the crystal structure of compound 15 was investigated and revealed that the title derivative is composed of two symmetrically independent molecules in the solid state with anti configuration the C=O versus P=O. NBO and AIM analyses were performed to investigate electronic aspects of hydrogen bonding of the crystal cluster, which play an extremely important role in biochemical systems.
